Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4703_RS08005 Genome accession   NZ_CP137100
Coordinates   1472225..1472914 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LYP     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1467225..1477914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS07980 gpsB 1467334..1467663 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R4703_RS07990 - 1468149..1469306 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  R4703_RS07995 mapZ 1469319..1470713 (+) 1395 WP_023396578.1 mid-cell-anchored protein MapZ -
  R4703_RS08000 gndA 1470789..1472213 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R4703_RS08005 covR 1472225..1472914 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R4703_RS08010 cbpC 1473013..1474032 (+) 1020 WP_000771049.1 choline-binding protein CbpC -
  R4703_RS08015 - 1474151..1475383 (-) 1233 WP_000765667.1 MFS transporter -
  R4703_RS08020 - 1475660..1476301 (-) 642 WP_231293594.1 lanthionine synthetase LanC family protein -
  R4703_RS08025 - 1476913..1477242 (+) 330 WP_000196978.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=895127 R4703_RS08005 WP_000518011.1 1472225..1472914(+) (covR) [Streptococcus pneumoniae strain LYP]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895127 R4703_RS08005 WP_000518011.1 1472225..1472914(+) (covR) [Streptococcus pneumoniae strain LYP]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467