Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R4714_RS07505 Genome accession   NZ_CP137099
Coordinates   1404685..1405374 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20824-4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1399685..1410374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS07480 gpsB 1399794..1400123 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R4714_RS07490 - 1400609..1401766 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  R4714_RS07495 mapZ 1401779..1403173 (+) 1395 WP_000039270.1 mid-cell-anchored protein MapZ -
  R4714_RS07500 gndA 1403249..1404673 (+) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  R4714_RS07505 covR 1404685..1405374 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  R4714_RS07510 - 1405472..1406374 (+) 903 WP_061636011.1 choline-binding protein CbpC -
  R4714_RS07515 cbpJ 1406393..1407391 (+) 999 WP_061636012.1 choline-binding protein CbpJ -
  R4714_RS07520 - 1407427..1408683 (-) 1257 WP_000436238.1 ISL3-like element IS1167A family transposase -
  R4714_RS07525 mvk 1408934..1409812 (+) 879 WP_050257859.1 mevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=895048 R4714_RS07505 WP_000518018.1 1404685..1405374(+) (covR) [Streptococcus pneumoniae strain 20824-4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=895048 R4714_RS07505 WP_000518018.1 1404685..1405374(+) (covR) [Streptococcus pneumoniae strain 20824-4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463