Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxO   Type   Regulator
Locus tag   R4535_RS04280 Genome accession   NZ_CP137091
Coordinates   918499..919866 (+) Length   455 a.a.
NCBI ID   WP_001888250.1    Uniprot ID   Q9KT84
Organism   Vibrio cholerae strain DL4211     
Function   promote HapR production (predicted from homology)   
Competence regulation

Genomic Context

Location: 913499..924866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4535_RS04265 (R4535_04260) - 913882..915270 (+) 1389 WP_407284729.1 IS4-like element ISVa18 family transposase -
  R4535_RS04275 (R4535_04270) uvrB 916039..918069 (+) 2031 WP_001961396.1 excinuclease ABC subunit UvrB -
  R4535_RS04280 (R4535_04275) luxO 918499..919866 (+) 1368 WP_001888250.1 quorum-sensing sigma-54 dependent transcriptional regulator LuxO Regulator
  R4535_RS04285 (R4535_04280) luxU 919870..920211 (+) 342 WP_001209531.1 quorum-sensing phosphorelay protein LuxU -
  R4535_RS04290 (R4535_04285) - 920200..921090 (-) 891 WP_000061070.1 YvcK family protein -
  R4535_RS04295 (R4535_04290) moaA 921397..922386 (+) 990 WP_076025718.1 GTP 3',8-cyclase MoaA -
  R4535_RS04300 (R4535_04295) moaB 922446..922958 (+) 513 WP_000509705.1 molybdenum cofactor biosynthesis protein B -
  R4535_RS04305 (R4535_04300) moaC 922969..923448 (+) 480 WP_000080913.1 cyclic pyranopterin monophosphate synthase MoaC -
  R4535_RS04310 (R4535_04305) moaD 923445..923690 (+) 246 WP_076025716.1 molybdopterin synthase sulfur carrier subunit -
  R4535_RS04315 (R4535_04310) moaE 923692..924153 (+) 462 WP_000350082.1 molybdopterin synthase catalytic subunit MoaE -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50839.12 Da        Isoelectric Point: 5.5755

>NTDB_id=894954 R4535_RS04280 WP_001888250.1 918499..919866(+) (luxO) [Vibrio cholerae strain DL4211]
MVEDTASVAALYRSYLTPLDIDINIVGTGRDAIESIGRREPDLILLDLRLPDMTGMDVLYAVKEKSPDVPIVFMTAHGSI
DTAVEAMRHGAQDFLIKPCEADRLRVTVNNAIRKASKLKNDVDNKNQNYQGFIGSSQTMQAVYRTIDSAASSKASIFITG
ESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATERQGAAEAADGGTLFLDELCEMDLDL
QTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRARGDDVIEIAYSLLGF
MSKEEGKDFVRLSAEVVERFRQYEWPGNVRQLQNVLRNVVVLNEGREITLDMLPPPLNQMSAPINRALPLAHENKVSVHE
IFPLWMTEKQAIEQAIEACDGNIPRAATYLDVSPSTIYRKLQTWNEKVKEKEKER

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=894954 R4535_RS04280 WP_001888250.1 918499..919866(+) (luxO) [Vibrio cholerae strain DL4211]
ATGGTAGAAGACACGGCATCGGTGGCGGCGCTGTATCGTTCTTACCTCACACCGCTGGATATTGATATCAATATCGTGGG
TACCGGACGCGATGCCATCGAGAGTATTGGCCGTCGCGAGCCTGACTTAATCCTGCTGGATTTACGTTTGCCAGATATGA
CGGGGATGGACGTACTCTATGCAGTGAAAGAGAAATCACCGGATGTGCCTATCGTGTTTATGACCGCGCATGGTTCGATT
GATACGGCGGTTGAAGCCATGCGTCATGGTGCGCAAGACTTTTTGATCAAGCCGTGTGAAGCGGACCGACTGCGAGTCAC
TGTGAATAATGCGATTCGCAAAGCCTCGAAACTCAAAAACGATGTTGATAATAAAAATCAAAACTATCAAGGCTTTATTG
GTAGCAGTCAAACCATGCAGGCGGTGTACCGCACCATTGACTCTGCGGCGAGCAGCAAAGCCAGTATTTTTATTACCGGC
GAAAGTGGTACCGGTAAAGAAGTGTGCGCGGAGGCGATTCATGCCGCGAGCAAGCGCGGAGATAAGCCATTTATCGCCAT
CAACTGTGCGGCCATTCCGAAAGATCTGATTGAAAGTGAGTTGTTTGGTCACGTTAAAGGGGCTTTTACCGGAGCGGCGA
CTGAGCGTCAAGGCGCGGCAGAAGCGGCTGATGGGGGAACCCTCTTTTTGGATGAATTGTGCGAAATGGATCTGGATCTG
CAGACCAAACTGCTGCGCTTCATCCAGACAGGGACATTCCAAAAAGTCGGCTCTTCCAAAATGAAAAGCGTGGATGTGCG
TTTTGTGTGTGCGACGAACCGCGATCCGTGGAAGGAAGTGCAAGAAGGGCGTTTTCGTGAAGACCTGTACTACCGCTTGT
ATGTGATCCCGCTGCATTTACCGCCATTGCGCGCGCGCGGTGATGATGTGATCGAGATTGCTTACTCACTGCTTGGCTTT
ATGTCCAAGGAAGAGGGCAAAGATTTTGTCCGTTTGTCGGCTGAAGTGGTGGAGCGTTTTCGTCAATACGAGTGGCCGGG
CAACGTGCGTCAATTGCAAAACGTTTTGCGCAACGTGGTCGTGCTCAATGAAGGTCGTGAAATCACCTTAGATATGCTGC
CTCCTCCTCTTAATCAAATGTCCGCGCCGATCAATCGGGCTTTACCGCTTGCGCATGAGAATAAAGTATCCGTGCATGAG
ATTTTTCCGCTATGGATGACCGAAAAACAAGCCATTGAACAAGCCATAGAAGCGTGTGATGGTAACATTCCCCGCGCCGC
GACCTATCTGGATGTCAGTCCATCAACCATCTATCGCAAGCTGCAAACTTGGAATGAAAAAGTGAAAGAAAAAGAGAAGG
AACGGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(404-442)

Sigma-54 interaction domain (Sigma54_activat)

(133-298)

Response regulator receiver domain (Response_reg)

(2-108)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9KT84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxO Vibrio cholerae strain A1552

100

100

1
  pilR Pseudomonas aeruginosa PAK

38.274

99.341

0.38