Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   AAYT23_RS08695 Genome accession   NZ_CP154877
Coordinates   1689781..1690401 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0H2URP6
Organism   Streptococcus pneumoniae strain 20234295     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1684781..1695401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS08670 (AAYT23_08655) recA 1685158..1686324 (-) 1167 WP_001085463.1 recombinase RecA -
  AAYT23_RS08675 (AAYT23_08660) cinA 1686379..1687635 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  AAYT23_RS08680 (AAYT23_08665) brpA 1687720..1688736 (-) 1017 WP_000239286.1 biofilm formation/cell division transcriptional regulator BrpA -
  AAYT23_RS08685 (AAYT23_08670) - 1688744..1689262 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  AAYT23_RS08690 (AAYT23_08675) tsaE 1689252..1689695 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  AAYT23_RS08695 (AAYT23_08680) comM 1689781..1690401 (-) 621 WP_000839908.1 hypothetical protein Regulator
  AAYT23_RS08700 (AAYT23_08685) - 1690784..1691647 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  AAYT23_RS08705 (AAYT23_08690) - 1691829..1691999 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  AAYT23_RS08710 (AAYT23_08695) pneA1 1692102..1692326 (+) 225 WP_000181086.1 two-peptide bacteriocin subunit PneA1 -
  AAYT23_RS08715 (AAYT23_08700) pneA2 1692333..1692521 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=894130 AAYT23_RS08695 WP_000839908.1 1689781..1690401(-) (comM) [Streptococcus pneumoniae strain 20234295]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=894130 AAYT23_RS08695 WP_000839908.1 1689781..1690401(-) (comM) [Streptococcus pneumoniae strain 20234295]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369