Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AAYT23_RS01750 Genome accession   NZ_CP154877
Coordinates   338071..338703 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234295     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 333071..343703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS01725 (AAYT23_01715) mvaD 333348..334301 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  AAYT23_RS01730 (AAYT23_01720) - 334288..335295 (+) 1008 WP_000562378.1 phosphomevalonate kinase -
  AAYT23_RS01735 (AAYT23_01725) fni 335279..336289 (+) 1011 WP_000210613.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AAYT23_RS01740 (AAYT23_01730) liaF 336367..337065 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  AAYT23_RS01745 (AAYT23_01735) - 337062..338057 (+) 996 WP_000743685.1 sensor histidine kinase -
  AAYT23_RS01750 (AAYT23_01740) vraR 338071..338703 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  AAYT23_RS01755 (AAYT23_01745) - 338704..338946 (+) 243 Protein_342 DNA alkylation repair protein -
  AAYT23_RS01760 (AAYT23_01750) - 338871..339473 (+) 603 Protein_343 DNA alkylation repair protein -
  AAYT23_RS01765 (AAYT23_01755) - 339932..340534 (+) 603 Protein_344 trypsin-like serine peptidase -
  AAYT23_RS01770 (AAYT23_01760) - 340890..341195 (+) 306 WP_025169150.1 tyrosine-type recombinase/integrase -
  AAYT23_RS01775 (AAYT23_01765) tig 341389..342672 (+) 1284 WP_000116473.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=894059 AAYT23_RS01750 WP_000698433.1 338071..338703(+) (vraR) [Streptococcus pneumoniae strain 20234295]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=894059 AAYT23_RS01750 WP_000698433.1 338071..338703(+) (vraR) [Streptococcus pneumoniae strain 20234295]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41