Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AAYT22_RS01755 Genome accession   NZ_CP154876
Coordinates   338170..338802 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 333170..343802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS01730 (AAYT22_01720) mvaD 333447..334400 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  AAYT22_RS01735 (AAYT22_01725) - 334387..335394 (+) 1008 WP_000562378.1 phosphomevalonate kinase -
  AAYT22_RS01740 (AAYT22_01730) fni 335378..336388 (+) 1011 WP_000210613.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AAYT22_RS01745 (AAYT22_01735) liaF 336466..337164 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  AAYT22_RS01750 (AAYT22_01740) - 337161..338156 (+) 996 WP_000743685.1 sensor histidine kinase -
  AAYT22_RS01755 (AAYT22_01745) vraR 338170..338802 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  AAYT22_RS01760 (AAYT22_01750) - 338803..339045 (+) 243 Protein_343 DNA alkylation repair protein -
  AAYT22_RS01765 (AAYT22_01755) - 338970..339572 (+) 603 Protein_344 DNA alkylation repair protein -
  AAYT22_RS01770 (AAYT22_01760) - 340031..340633 (+) 603 Protein_345 trypsin-like serine peptidase -
  AAYT22_RS01775 (AAYT22_01765) - 340989..341294 (+) 306 WP_025169150.1 tyrosine-type recombinase/integrase -
  AAYT22_RS01780 (AAYT22_01770) tig 341488..342771 (+) 1284 WP_000116473.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=893939 AAYT22_RS01755 WP_000698433.1 338170..338802(+) (vraR) [Streptococcus pneumoniae strain 20155336]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=893939 AAYT22_RS01755 WP_000698433.1 338170..338802(+) (vraR) [Streptococcus pneumoniae strain 20155336]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41