Detailed information NTG0893204

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R1Y14_RS00365
• Genome accession: NZ_CP136899
• Coordinates: 58119..59156 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727275.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ST62
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 53119..64156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R1Y14_RS00340 (R1Y14_00340)	-	53858..55189 (-)	1332	WP_000390042.1	hemolysin family protein	-
R1Y14_RS00345 (R1Y14_00345)	endA	55480..56304 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
R1Y14_RS00350 (R1Y14_00350)	-	56343..56531 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R1Y14_RS00355 (R1Y14_00355)	murA	56524..57807 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R1Y14_RS00360 (R1Y14_00360)	-	57831..58061 (-)	231	WP_000250384.1	DUF1146 family protein	-
R1Y14_RS00365 (R1Y14_00365)	sepM	58119..59156 (-)	1038	WP_000727275.1	SepM family pheromone-processing serine protease	Regulator
R1Y14_RS00370 (R1Y14_00370)	coaD	59140..59628 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
R1Y14_RS00375 (R1Y14_00375)	rsmD	59618..60157 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R1Y14_RS00380 (R1Y14_00380)	asnA	60222..61214 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R1Y14_RS00385 (R1Y14_00385)	-	61325..62008 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R1Y14_RS00390 (R1Y14_00390)	-	62064..62804 (-)	741	WP_000152681.1	RNA methyltransferase	-
R1Y14_RS00395 (R1Y14_00395)	-	62838..63116 (+)	279	WP_001174613.1	acylphosphatase	-
R1Y14_RS00400 (R1Y14_00400)	yidC	63194..64120 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=893204 R1Y14_RS00365 WP_000727275.1 58119..59156(-) (sepM) [Streptococcus pneumoniae strain ST62]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKEILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=893204 R1Y14_RS00365 WP_000727275.1 58119..59156(-) (sepM) [Streptococcus pneumoniae strain ST62]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGAGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588