Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R1Y14_RS00345 Genome accession   NZ_CP136899
Coordinates   55480..56304 (-) Length   274 a.a.
NCBI ID   WP_001036779.1    Uniprot ID   P0A3S3
Organism   Streptococcus pneumoniae strain ST62     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 50480..61304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y14_RS00340 (R1Y14_00340) - 53858..55189 (-) 1332 WP_000390042.1 hemolysin family protein -
  R1Y14_RS00345 (R1Y14_00345) endA 55480..56304 (-) 825 WP_001036779.1 DNA-entry nuclease EndA Machinery gene
  R1Y14_RS00350 (R1Y14_00350) - 56343..56531 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R1Y14_RS00355 (R1Y14_00355) murA 56524..57807 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R1Y14_RS00360 (R1Y14_00360) - 57831..58061 (-) 231 WP_000250384.1 DUF1146 family protein -
  R1Y14_RS00365 (R1Y14_00365) sepM 58119..59156 (-) 1038 WP_000727275.1 SepM family pheromone-processing serine protease Regulator
  R1Y14_RS00370 (R1Y14_00370) coaD 59140..59628 (-) 489 WP_001280742.1 pantetheine-phosphate adenylyltransferase -
  R1Y14_RS00375 (R1Y14_00375) rsmD 59618..60157 (-) 540 WP_000706962.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R1Y14_RS00380 (R1Y14_00380) asnA 60222..61214 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29890.57 Da        Isoelectric Point: 10.1197

>NTDB_id=893203 R1Y14_RS00345 WP_001036779.1 55480..56304(-) (endA) [Streptococcus pneumoniae strain ST62]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=893203 R1Y14_RS00345 WP_001036779.1 55480..56304(-) (endA) [Streptococcus pneumoniae strain ST62]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCCGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3OWV

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

100

100

1
  endA Streptococcus pneumoniae D39

100

100

1
  endA Streptococcus pneumoniae R6

100

100

1
  endA Streptococcus pneumoniae TIGR4

100

100

1