Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R1Y14_RS00295 Genome accession   NZ_CP136899
Coordinates   39539..40159 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain ST62     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 34539..45159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y14_RS00270 (R1Y14_00270) recA 34916..36082 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R1Y14_RS00275 (R1Y14_00275) cinA 36137..37393 (-) 1257 WP_000642708.1 competence/damage-inducible protein A Machinery gene
  R1Y14_RS00280 (R1Y14_00280) brpA 37478..38494 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R1Y14_RS00285 (R1Y14_00285) - 38502..39020 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R1Y14_RS00290 (R1Y14_00290) tsaE 39010..39453 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R1Y14_RS00295 (R1Y14_00295) comM 39539..40159 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R1Y14_RS00300 (R1Y14_00300) - 40542..41405 (-) 864 WP_001093618.1 helix-turn-helix domain-containing protein -
  R1Y14_RS00305 (R1Y14_00305) - 41751..43766 (+) 2016 WP_000732380.1 DUF1430 domain-containing protein -
  R1Y14_RS00310 (R1Y14_00310) - 43768..44400 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -
  R1Y14_RS00315 (R1Y14_00315) - 44541..44819 (+) 279 WP_000712962.1 hypothetical protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=893202 R1Y14_RS00295 WP_000839908.1 39539..40159(-) (comM) [Streptococcus pneumoniae strain ST62]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=893202 R1Y14_RS00295 WP_000839908.1 39539..40159(-) (comM) [Streptococcus pneumoniae strain ST62]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369