Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   R1T10_RS02935 Genome accession   NZ_CP136807
Coordinates   563100..563960 (-) Length   286 a.a.
NCBI ID   WP_002226036.1    Uniprot ID   A0A112F5U3
Organism   Neisseria meningitidis NMB     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 558100..568960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS02905 ispB 558586..559560 (+) 975 WP_002216396.1 octaprenyl diphosphate synthase -
  R1T10_RS02910 - 559565..560011 (+) 447 WP_002233503.1 DUF441 domain-containing protein -
  R1T10_RS02920 pilF 560503..562179 (+) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  R1T10_RS02925 - 562264..562473 (-) 210 WP_002226032.1 DNA gyrase inhibitor YacG -
  R1T10_RS02930 coaE 562466..563098 (-) 633 WP_002226034.1 dephospho-CoA kinase -
  R1T10_RS02935 pilD 563100..563960 (-) 861 WP_002226036.1 A24 family peptidase Machinery gene
  R1T10_RS02940 pilG 564034..565266 (-) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  R1T10_RS02945 pgi 565776..567419 (+) 1644 WP_002244409.1 glucose-6-phosphate isomerase -
  R1T10_RS02950 - 567389..567619 (+) 231 WP_002212338.1 hypothetical protein -
  R1T10_RS02955 dapD 567629..568450 (+) 822 WP_002226039.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31389.43 Da        Isoelectric Point: 8.2213

>NTDB_id=892840 R1T10_RS02935 WP_002226036.1 563100..563960(-) (pilD) [Neisseria meningitidis NMB]
MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=892840 R1T10_RS02935 WP_002226036.1 563100..563960(-) (pilD) [Neisseria meningitidis NMB]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGACAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A112F5U3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.789

99.65

0.955
  pilD Vibrio cholerae strain A1552

44.097

100

0.444
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434
  pilD Vibrio campbellii strain DS40M4

44.565

96.503

0.43