Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   R1T10_RS01055 Genome accession   NZ_CP136807
Coordinates   196309..196773 (-) Length   154 a.a.
NCBI ID   WP_011798742.1    Uniprot ID   -
Organism   Neisseria meningitidis NMB     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 187602..202989 196309..196773 within 0


Gene organization within MGE regions


Location: 187602..202989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS01015 - 187602..188759 (-) 1158 WP_017201173.1 DUF6716 putative glycosyltransferase -
  R1T10_RS01020 galE 188936..189955 (+) 1020 WP_002225925.1 UDP-glucose 4-epimerase GalE -
  R1T10_RS01025 rfbB 189956..191038 (+) 1083 WP_002225918.1 dTDP-glucose 4,6-dehydratase -
  R1T10_RS01030 rfbA 191101..191967 (+) 867 WP_002226897.1 glucose-1-phosphate thymidylyltransferase RfbA -
  R1T10_RS01035 rfbC 192021..192578 (+) 558 WP_002224368.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  R1T10_RS01040 - 192622..194640 (-) 2019 WP_002224367.1 oligopeptide transporter, OPT family -
  R1T10_RS01045 dnaJ 194836..195957 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  R1T10_RS01050 - 196039..196197 (-) 159 WP_002215272.1 hypothetical protein -
  R1T10_RS01055 comE 196309..196773 (-) 465 WP_011798742.1 ComEA family DNA-binding protein Machinery gene
  R1T10_RS01085 dksA 202573..202989 (-) 417 WP_002238569.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16605.84 Da        Isoelectric Point: 10.8773

>NTDB_id=892828 R1T10_RS01055 WP_011798742.1 196309..196773(-) (comE) [Neisseria meningitidis NMB]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=892828 R1T10_RS01055 WP_011798742.1 196309..196773(-) (comE) [Neisseria meningitidis NMB]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74