Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RYQ61_RS01345 Genome accession   NZ_CP136799
Coordinates   257044..257733 (-) Length   229 a.a.
NCBI ID   WP_003071837.1    Uniprot ID   A0A3R9LG80
Organism   Streptococcus intermedius strain XH2169     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 252044..262733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS01325 (RYQ61_01325) - 252534..253016 (+) 483 WP_102567840.1 streptodornase -
  RYQ61_RS01330 (RYQ61_01330) - 253067..253882 (-) 816 WP_009569215.1 endonuclease/exonuclease/phosphatase family protein -
  RYQ61_RS01335 (RYQ61_01335) - 253900..256089 (-) 2190 WP_150225492.1 PTS transporter subunit IIBC -
  RYQ61_RS01340 (RYQ61_01340) - 256288..256737 (-) 450 Protein_269 PTS glucose transporter subunit IIA -
  RYQ61_RS01345 (RYQ61_01345) covR 257044..257733 (-) 690 WP_003071837.1 response regulator transcription factor Regulator
  RYQ61_RS01350 (RYQ61_01350) gndA 257742..259166 (-) 1425 WP_102568437.1 NADP-dependent phosphogluconate dehydrogenase -
  RYQ61_RS01355 (RYQ61_01355) - 259258..259794 (-) 537 WP_003038571.1 DUF177 domain-containing protein -
  RYQ61_RS01360 (RYQ61_01360) - 259982..261208 (+) 1227 WP_102568438.1 transporter -
  RYQ61_RS01365 (RYQ61_01365) htpX 261311..262207 (-) 897 WP_102568439.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26549.61 Da        Isoelectric Point: 6.5002

>NTDB_id=892690 RYQ61_RS01345 WP_003071837.1 257044..257733(-) (covR) [Streptococcus intermedius strain XH2169]
MGKRILLVENEKKLAQFISLELQNEGYRVDLFETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVGKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=892690 RYQ61_RS01345 WP_003071837.1 257044..257733(-) (covR) [Streptococcus intermedius strain XH2169]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTTTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTAAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGGAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCTGTCGAGACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACTGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-82)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LG80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45