Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AAEU35_RS02600 Genome accession   NZ_CP152294
Coordinates   549871..550500 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain Q13     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 544871..555500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAEU35_RS02575 - 545800..547044 (-) 1245 WP_058223110.1 FtsW/RodA/SpoVE family cell cycle protein -
  AAEU35_RS02580 - 547266..547871 (-) 606 WP_012897545.1 TVP38/TMEM64 family protein -
  AAEU35_RS02585 - 547868..548299 (-) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  AAEU35_RS02590 - 548301..548891 (-) 591 WP_012897543.1 peptidylprolyl isomerase -
  AAEU35_RS02595 - 548994..549800 (-) 807 WP_058223111.1 Cof-type HAD-IIB family hydrolase -
  AAEU35_RS02600 vraR 549871..550500 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  AAEU35_RS02605 - 550528..551526 (-) 999 WP_012897540.1 sensor histidine kinase -
  AAEU35_RS02610 liaF 551523..552152 (-) 630 WP_003131399.1 cell wall-active antibiotics response protein LiaF -
  AAEU35_RS02615 rpsN 552319..552588 (-) 270 WP_010905608.1 30S ribosomal protein S14 -
  AAEU35_RS02620 - 552686..553693 (-) 1008 WP_342630384.1 LCP family protein -
  AAEU35_RS02625 - 553629..553985 (-) 357 WP_342630387.1 hypothetical protein -
  AAEU35_RS02630 - 554016..555215 (-) 1200 WP_058208370.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=891790 AAEU35_RS02600 WP_003131402.1 549871..550500(-) (vraR) [Lactococcus lactis strain Q13]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=891790 AAEU35_RS02600 WP_003131402.1 549871..550500(-) (vraR) [Lactococcus lactis strain Q13]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCAGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATCGCATCTGCGATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416