Detailed information NTG0891480

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: AAGT87_RS18045
• Genome accession: NZ_CP152071
• Coordinates: 2889542..2890822 (+)
• Length: 426 a.a.
• NCBI ID: WP_000130332.1
• Uniprot ID: A0AAU8WEE3
• Organism: Vibrio cholerae strain Sudan_2019_18
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2884542..2895822

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAGT87_RS18025 (AAGT87_18030)	-	2885152..2886930 (-)	1779	WP_032470662.1	sensor histidine kinase	-
AAGT87_RS18030 (AAGT87_18035)	-	2886920..2887138 (+)	219	WP_001881672.1	hypothetical protein	-
AAGT87_RS18035 (AAGT87_18040)	tig	2887429..2888730 (+)	1302	WP_001198446.1	trigger factor	-
AAGT87_RS18040 (AAGT87_18045)	clpP	2888836..2889462 (+)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
AAGT87_RS18045 (AAGT87_18050)	clpX	2889542..2890822 (+)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
AAGT87_RS18050 (AAGT87_18055)	lon	2890945..2893305 (+)	2361	WP_353495306.1	endopeptidase La	-
AAGT87_RS18055 (AAGT87_18060)	-	2893489..2893761 (+)	273	WP_001044516.1	HU family DNA-binding protein	-
AAGT87_RS18060 (AAGT87_18065)	ppiD	2893914..2895773 (+)	1860	WP_341264862.1	peptidylprolyl isomerase	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46490.23 Da
• Isoelectric Point: 4.7780

>NTDB_id=891480 AAGT87_RS18045 WP_000130332.1 2889542..2890822(+) (clpX) [Vibrio cholerae strain Sudan_2019_18]
MTDKSKEGGSSKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESAALPTPRKIREHLDDYVI
GQEHAKKVLAVAVYNHYKRLRNGDTTSEGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNSKTLSELFTQVEPEDLVKYGLIPEFIGRLPVTATLTELD
EAALIQILCEPKNALTKQYAALFELENVDLEFREDALKAIAAKAMKRKTGARGLRSILEAVLLETMYELPSMEEVSKVVI
DESVINGESAPLLIYSANESQAAGAE

Nucleotide

• Length: 1281 bp

>NTDB_id=891480 AAGT87_RS18045 WP_000130332.1 2889542..2890822(+) (clpX) [Vibrio cholerae strain Sudan_2019_18]
ATGACAGACAAAAGCAAAGAGGGCGGTAGTAGTAAACTGCTGTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAACTGATCGCAGGTCCGTCCGTGTATATTTGTGATGAGTGCGTTGATTTATGCAACGACATCATCCGCGAAGAGATCA
AAGATGTTCTGCCAAAAAAGGAATCAGCGGCGTTACCGACGCCAAGAAAGATTCGTGAACATCTCGACGATTATGTGATT
GGTCAAGAACACGCCAAAAAAGTGCTAGCCGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACTAG
CGAAGGCGTTGAGCTGGGCAAGAGTAACATTTTGCTGATTGGCCCAACGGGTAGCGGTAAAACACTACTGGCTGAAACGC
TGGCGCGTTTGCTGGATGTGCCATTTACCATGGCGGATGCGACCACATTAACCGAAGCGGGTTATGTGGGCGAAGATGTA
GAAAATATCATTCAAAAGCTGCTGCAAAAATGCGATTACGATGTTGCAAAAGCGGAGCGTGGTATCGTCTATATCGATGA
AATTGACAAAATTTCTCGTAAGTCTGAAAACCCATCCATCACACGTGACGTGTCGGGTGAAGGGGTTCAGCAAGCGCTGT
TAAAACTGATTGAAGGTACAGTTGCTTCGGTTCCACCACAAGGTGGCCGTAAACATCCTCAGCAGGAATTCCTGCAAGTC
GACACCTCAAAAATCCTATTTATCTGTGGTGGCGCGTTTGCTGGCCTAGATAAAGTGATTGAACAGCGTGTTGCGACAGG
GACTGGTATCGGTTTTGGCGCGGATGTGCGTTCTAAAGACAACAGCAAAACCTTGAGCGAACTGTTTACTCAGGTTGAAC
CTGAAGATTTGGTGAAATACGGTTTGATCCCAGAGTTCATTGGTCGTCTGCCTGTTACGGCAACGCTGACTGAACTGGAT
GAAGCGGCATTGATTCAAATTCTGTGTGAACCAAAGAATGCACTGACCAAACAGTATGCGGCGTTGTTTGAACTGGAAAA
CGTTGATCTGGAGTTTCGTGAAGATGCGCTGAAAGCGATTGCCGCTAAAGCGATGAAGCGTAAAACCGGTGCGCGTGGTC
TACGTTCAATCCTTGAAGCAGTTCTACTGGAAACCATGTATGAACTGCCTTCAATGGAAGAGGTCAGCAAGGTGGTGATT
GACGAATCTGTGATCAACGGAGAGTCCGCACCGCTACTGATTTACAGCGCTAATGAGAGCCAAGCCGCTGGTGCGGAGTA
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (319-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (114-312)

3D structure

• AlphaFold DB: A0AAU8WEE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	58.706	94.366	0.554
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.333	95.07	0.507