Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AAGG04_RS03075 Genome accession   NZ_CP151931
Coordinates   644837..645493 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 8178 isolate T2213     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 639837..650493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAGG04_RS03045 (AAGG04_03040) dcyD 640716..641702 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  AAGG04_RS03050 (AAGG04_03045) tcyL 641717..642385 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AAGG04_RS03055 (AAGG04_03050) tcyN 642382..643134 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AAGG04_RS03060 (AAGG04_03055) sdiA 643364..644086 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  AAGG04_RS03065 (AAGG04_03060) yecF 644154..644378 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AAGG04_RS03070 (AAGG04_03065) yecU 644365..644541 (-) 177 WP_001307856.1 protein YecU -
  AAGG04_RS03075 (AAGG04_03070) letA 644837..645493 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AAGG04_RS03080 (AAGG04_03075) uvrC 645490..647322 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AAGG04_RS03085 (AAGG04_03080) pgsA 647379..647927 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AAGG04_RS03105 (AAGG04_03100) yecA 648576..649241 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=891076 AAGG04_RS03075 WP_000611328.1 644837..645493(+) (letA) [Escherichia coli strain 8178 isolate T2213]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=891076 AAGG04_RS03075 WP_000611328.1 644837..645493(+) (letA) [Escherichia coli strain 8178 isolate T2213]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCTACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482