Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   F6I35_RS08310 Genome accession   NZ_CP136160
Coordinates   1584910..1585599 (-) Length   229 a.a.
NCBI ID   WP_101800963.1    Uniprot ID   -
Organism   Streptococcus anginosus strain UMB8616     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1579910..1590599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS08290 (F6I35_0008285) nrdR 1580395..1580868 (-) 474 WP_024052506.1 transcriptional regulator NrdR -
  F6I35_RS08295 (F6I35_0008290) - 1581034..1581630 (+) 597 Protein_1603 hypothetical protein -
  F6I35_RS08300 (F6I35_0008295) - 1581678..1582493 (-) 816 WP_024052509.1 endonuclease/exonuclease/phosphatase family protein -
  F6I35_RS08305 (F6I35_0008300) - 1582510..1584699 (-) 2190 WP_150867147.1 PTS transporter subunit IIBC -
  F6I35_RS08310 (F6I35_0008305) covR 1584910..1585599 (-) 690 WP_101800963.1 DNA-binding response regulator Regulator
  F6I35_RS08315 (F6I35_0008310) gndA 1585608..1587032 (-) 1425 WP_024052512.1 NADP-dependent phosphogluconate dehydrogenase -
  F6I35_RS08320 (F6I35_0008315) - 1587330..1587953 (-) 624 WP_150867150.1 DNA alkylation repair protein -
  F6I35_RS08325 (F6I35_0008320) - 1588004..1588540 (-) 537 WP_070812069.1 DUF177 domain-containing protein -
  F6I35_RS08330 (F6I35_0008325) - 1588653..1589510 (+) 858 Protein_1610 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26448.51 Da        Isoelectric Point: 6.2732

>NTDB_id=888972 F6I35_RS08310 WP_101800963.1 1584910..1585599(-) (covR) [Streptococcus anginosus strain UMB8616]
MGKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKMDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=888972 F6I35_RS08310 WP_101800963.1 1584910..1585599(-) (covR) [Streptococcus anginosus strain UMB8616]
ATGGGGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATGGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45