Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   F6I35_RS04490 Genome accession   NZ_CP136160
Coordinates   853988..855220 (+) Length   410 a.a.
NCBI ID   WP_150867011.1    Uniprot ID   A0AAW5THJ7
Organism   Streptococcus anginosus strain UMB8616     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 852240..863082 853988..855220 within 0


Gene organization within MGE regions


Location: 852240..863082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS04475 (F6I35_0004475) - 852240..853079 (+) 840 WP_024052282.1 thymidylate synthase -
  F6I35_RS04480 (F6I35_0004480) - 853264..853776 (+) 513 WP_024052281.1 dihydrofolate reductase -
  F6I35_RS04485 (F6I35_0004485) - 853776..853949 (+) 174 WP_003024903.1 hypothetical protein -
  F6I35_RS04490 (F6I35_0004490) clpX 853988..855220 (+) 1233 WP_150867011.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  F6I35_RS04495 (F6I35_0004495) yihA 855232..855819 (+) 588 WP_024052279.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  F6I35_RS04500 (F6I35_0004500) - 856000..856707 (+) 708 WP_003024892.1 glucosaminidase domain-containing protein -
  F6I35_RS04505 (F6I35_0004505) - 856890..858635 (+) 1746 WP_070815110.1 ABC transporter ATP-binding protein -
  F6I35_RS04510 (F6I35_0004510) - 858616..860364 (+) 1749 WP_070815111.1 ABC transporter ATP-binding protein -
  F6I35_RS04515 (F6I35_0004515) - 860385..861920 (-) 1536 WP_070815112.1 ATP-binding cassette domain-containing protein -
  F6I35_RS04520 (F6I35_0004520) - 862342..863082 (-) 741 WP_070241651.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45688.21 Da        Isoelectric Point: 4.4242

>NTDB_id=888965 F6I35_RS04490 WP_150867011.1 853988..855220(+) (clpX) [Streptococcus anginosus strain UMB8616]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREEEDDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=888965 F6I35_RS04490 WP_150867011.1 853988..855220(+) (clpX) [Streptococcus anginosus strain UMB8616]
ATGCCTACAAATCGTACGAATGAAATGATGGTTTATTGCTCTTTTTGTGGTAAAAGCCAAGAAGAAGTCCAAAAAATTAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGCGTGGAATTAGCGCAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TACTAGCGGACTTGTCAGAAGTGCCAAAACCGCAAGAACTACTCAATATTTTGAATCATTATGTGATTGGGCAAGACCGT
GCTAAGCGAGCATTGGCTGTTGCTGTATACAATCACTATAAACGTATCAATTTTCACGATAATCGTGAAGAAGAGGATGA
TGTCGAATTACAAAAATCCAATATTCTTATGATTGGGCCAACTGGTTCTGGTAAGACTTTTCTTGCTCAAACCTTGGCGA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCAGAACGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAACGTGTCTATTACTCGCGATGTGTCTGGTGAAGGCGTTCAGCAAGCGCTCCTCAAGA
TTATTGAAGGAACTGTAGCCAGCGTACCTCCGCAAGGCGGTCGCAAGCACCCTCAACAAGAAATGATTCAAGTAGATACC
AAGAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAATAATAAAGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGTTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTGACAGTTGATGATTTGGTGCGA
ATCCTGCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTCCTTTCTTATGACGATGTTAAACTAGAGTTTGA
TGATGATGCTCTTCAGGAAATTGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCAATCATTGAGG
AAACTATGATGGATGTTATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATTACCAAGGAAGCAGTTGAT
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.049

0.571