Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   F6I35_RS02725 Genome accession   NZ_CP136160
Coordinates   489991..491046 (+) Length   351 a.a.
NCBI ID   WP_024052081.1    Uniprot ID   A0A413KQY5
Organism   Streptococcus anginosus strain UMB8616     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 484991..496046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS02695 (F6I35_0002695) - 485512..486147 (-) 636 WP_024052085.1 YigZ family protein -
  F6I35_RS02700 (F6I35_0002700) comFA/cflA 486204..487505 (+) 1302 WP_024052084.1 DEAD/DEAH box helicase Machinery gene
  F6I35_RS02705 (F6I35_0002705) comFC/cflB 487502..488167 (+) 666 WP_024052083.1 ComF family protein Machinery gene
  F6I35_RS02710 (F6I35_0002710) hpf 488245..488787 (+) 543 WP_003025754.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  F6I35_RS02715 (F6I35_0002715) rsmD 488975..489523 (+) 549 WP_171021853.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  F6I35_RS02720 (F6I35_0002720) coaD 489513..490010 (+) 498 WP_021001374.1 pantetheine-phosphate adenylyltransferase -
  F6I35_RS02725 (F6I35_0002725) sepM 489991..491046 (+) 1056 WP_024052081.1 SepM family pheromone-processing serine protease Regulator
  F6I35_RS02730 (F6I35_0002730) - 491185..491748 (+) 564 WP_024052080.1 YutD family protein -
  F6I35_RS02735 (F6I35_0002735) rlmN 491789..492871 (+) 1083 WP_024052079.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  F6I35_RS02740 (F6I35_0002740) - 492864..493394 (+) 531 WP_024052078.1 VanZ family protein -
  F6I35_RS02745 (F6I35_0002745) trpB 493755..494963 (+) 1209 Protein_500 tryptophan synthase subunit beta -
  F6I35_RS02750 (F6I35_0002750) cclA/cilC 495124..495783 (-) 660 WP_024052075.1 prepilin peptidase Machinery gene

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38290.25 Da        Isoelectric Point: 10.1906

>NTDB_id=888951 F6I35_RS02725 WP_024052081.1 489991..491046(+) (sepM) [Streptococcus anginosus strain UMB8616]
MEKPRNKFKKWPIIAVVGVILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATLAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=888951 F6I35_RS02725 WP_024052081.1 489991..491046(+) (sepM) [Streptococcus anginosus strain UMB8616]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGGTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCCTCGCTCATTTGGTTTATGCTTGGCTG
ACACCTTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGAGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-307)

PDZ domain (PDZ_2)

(133-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQY5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

64.223

97.151

0.624