Detailed information
Bioinformatically predicted
Overview
| Name | comGE/cglE | Type | Machinery gene |
| Locus tag | F6I35_RS01595 | Genome accession | NZ_CP136160 |
| Coordinates | 267867..268160 (+) | Length | 97 a.a. |
| NCBI ID | WP_024053127.1 | Uniprot ID | A0A412PLL4 |
| Organism | Streptococcus anginosus strain UMB8616 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 231310..280331 | 267867..268160 | within | 0 |
Gene organization within MGE regions
Location: 231310..280331
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F6I35_RS01335 (F6I35_0001335) | - | 231310..232755 (-) | 1446 | WP_150867047.1 | recombinase family protein | - |
| F6I35_RS01340 (F6I35_0001340) | - | 232903..233556 (-) | 654 | WP_150867045.1 | SHOCT domain-containing protein | - |
| F6I35_RS01345 (F6I35_0001345) | - | 233571..234374 (-) | 804 | WP_143876462.1 | S24 family peptidase | - |
| F6I35_RS01350 (F6I35_0001350) | - | 234544..234780 (+) | 237 | WP_191621614.1 | DUF739 family protein | - |
| F6I35_RS01355 (F6I35_0001355) | - | 234793..235524 (+) | 732 | WP_191621613.1 | phage antirepressor KilAC domain-containing protein | - |
| F6I35_RS01360 (F6I35_0001360) | - | 235589..235747 (+) | 159 | WP_181877640.1 | BOW99_gp33 family protein | - |
| F6I35_RS01365 (F6I35_0001365) | - | 235757..236119 (+) | 363 | WP_115283070.1 | helix-turn-helix domain-containing protein | - |
| F6I35_RS10800 | - | 236123..236206 (-) | 84 | WP_143876768.1 | pentapeptide repeat-containing protein | - |
| F6I35_RS01370 (F6I35_0001370) | - | 236359..236622 (+) | 264 | WP_150867043.1 | hypothetical protein | - |
| F6I35_RS01375 (F6I35_0001375) | - | 236622..236882 (+) | 261 | WP_181877641.1 | hypothetical protein | - |
| F6I35_RS01380 (F6I35_0001380) | - | 236893..237024 (+) | 132 | WP_258861403.1 | hypothetical protein | - |
| F6I35_RS01385 (F6I35_0001385) | bet | 237204..238046 (+) | 843 | WP_115283073.1 | phage recombination protein Bet | - |
| F6I35_RS01390 (F6I35_0001390) | - | 238056..239084 (+) | 1029 | WP_115283074.1 | DUF1351 domain-containing protein | - |
| F6I35_RS01395 (F6I35_0001395) | - | 239087..239350 (+) | 264 | WP_115283075.1 | hypothetical protein | - |
| F6I35_RS01400 (F6I35_0001400) | - | 239359..239679 (+) | 321 | WP_115283076.1 | hypothetical protein | - |
| F6I35_RS01405 (F6I35_0001405) | - | 239676..239921 (+) | 246 | WP_150867041.1 | sporulation protein Cse60 | - |
| F6I35_RS01410 (F6I35_0001410) | ssb | 240008..240481 (+) | 474 | WP_115283078.1 | single-stranded DNA-binding protein | Machinery gene |
| F6I35_RS01415 (F6I35_0001415) | - | 240491..241291 (+) | 801 | WP_115283079.1 | DNA methyltransferase | - |
| F6I35_RS01420 (F6I35_0001420) | - | 241281..241610 (+) | 330 | WP_115283080.1 | hypothetical protein | - |
| F6I35_RS01425 (F6I35_0001425) | - | 241607..242035 (+) | 429 | WP_150867039.1 | RusA family crossover junction endodeoxyribonuclease | - |
| F6I35_RS01430 (F6I35_0001430) | - | 242068..242343 (+) | 276 | WP_258861423.1 | DUF1372 family protein | - |
| F6I35_RS10805 | - | 242348..242473 (+) | 126 | WP_412103708.1 | hypothetical protein | - |
| F6I35_RS01435 (F6I35_0001435) | - | 242454..242660 (+) | 207 | WP_142743523.1 | hypothetical protein | - |
| F6I35_RS01440 (F6I35_0001440) | - | 242641..242895 (+) | 255 | WP_115283085.1 | hypothetical protein | - |
| F6I35_RS01445 (F6I35_0001445) | - | 242885..243136 (+) | 252 | WP_115283086.1 | hypothetical protein | - |
| F6I35_RS01450 (F6I35_0001450) | - | 243215..243637 (+) | 423 | WP_150867037.1 | DUF1492 domain-containing protein | - |
| F6I35_RS01455 (F6I35_0001455) | terS | 243878..244609 (+) | 732 | WP_115283088.1 | phage terminase small subunit | - |
| F6I35_RS01460 (F6I35_0001460) | - | 244578..245876 (+) | 1299 | WP_115283089.1 | PBSX family phage terminase large subunit | - |
| F6I35_RS01465 (F6I35_0001465) | - | 245888..247399 (+) | 1512 | WP_286048924.1 | phage portal protein | - |
| F6I35_RS01470 (F6I35_0001470) | - | 247404..249053 (+) | 1650 | WP_143876463.1 | phage minor capsid protein | - |
| F6I35_RS01475 (F6I35_0001475) | - | 249050..249331 (+) | 282 | WP_115283092.1 | hypothetical protein | - |
| F6I35_RS01480 (F6I35_0001480) | - | 249376..249603 (+) | 228 | WP_115283093.1 | hypothetical protein | - |
| F6I35_RS01485 (F6I35_0001485) | - | 249744..250307 (+) | 564 | WP_115283094.1 | phage scaffolding protein | - |
| F6I35_RS01490 (F6I35_0001490) | - | 250328..251197 (+) | 870 | WP_115283095.1 | capsid protein | - |
| F6I35_RS01495 (F6I35_0001495) | - | 251212..251370 (+) | 159 | WP_181877642.1 | hypothetical protein | - |
| F6I35_RS01500 (F6I35_0001500) | - | 251376..251573 (+) | 198 | WP_115283096.1 | hypothetical protein | - |
| F6I35_RS01505 (F6I35_0001505) | - | 251588..251995 (+) | 408 | WP_143876464.1 | hypothetical protein | - |
| F6I35_RS01510 (F6I35_0001510) | - | 251982..252323 (+) | 342 | WP_115283098.1 | putative minor capsid protein | - |
| F6I35_RS01515 (F6I35_0001515) | - | 252323..252685 (+) | 363 | WP_115283099.1 | minor capsid protein | - |
| F6I35_RS01520 (F6I35_0001520) | - | 252682..253083 (+) | 402 | WP_115283100.1 | minor capsid protein | - |
| F6I35_RS01525 (F6I35_0001525) | - | 253084..253545 (+) | 462 | WP_115283101.1 | phage tail tube protein | - |
| F6I35_RS01530 (F6I35_0001530) | - | 253607..253966 (+) | 360 | WP_115283102.1 | hypothetical protein | - |
| F6I35_RS01535 (F6I35_0001535) | - | 253968..254567 (+) | 600 | WP_115283103.1 | Gp15 family bacteriophage protein | - |
| F6I35_RS01540 (F6I35_0001540) | - | 254588..258346 (+) | 3759 | WP_150867035.1 | tape measure protein | - |
| F6I35_RS01545 (F6I35_0001545) | - | 258346..259839 (+) | 1494 | WP_150867033.1 | distal tail protein Dit | - |
| F6I35_RS01550 (F6I35_0001550) | - | 259843..262812 (+) | 2970 | WP_150867031.1 | phage tail spike protein | - |
| F6I35_RS01555 (F6I35_0001555) | - | 262812..264851 (+) | 2040 | WP_150867029.1 | DUF859 family phage minor structural protein | - |
| F6I35_RS01560 (F6I35_0001560) | - | 264864..265466 (+) | 603 | WP_150867027.1 | DUF1366 domain-containing protein | - |
| F6I35_RS01565 (F6I35_0001565) | - | 265484..265789 (+) | 306 | WP_049507630.1 | hypothetical protein | - |
| F6I35_RS01570 (F6I35_0001570) | - | 265801..266133 (+) | 333 | WP_049507631.1 | phage holin | - |
| F6I35_RS01575 (F6I35_0001575) | - | 266135..266881 (+) | 747 | WP_150867025.1 | CHAP domain-containing protein | - |
| F6I35_RS01580 (F6I35_0001580) | - | 266997..267236 (+) | 240 | WP_150867023.1 | hypothetical protein | - |
| F6I35_RS01585 (F6I35_0001585) | comYC | 267238..267507 (+) | 270 | WP_003039250.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| F6I35_RS01590 (F6I35_0001590) | comYD | 267467..267895 (+) | 429 | WP_024053128.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| F6I35_RS01595 (F6I35_0001595) | comGE/cglE | 267867..268160 (+) | 294 | WP_024053127.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| F6I35_RS01600 (F6I35_0001600) | comGF/cglF | 268144..268581 (+) | 438 | WP_024053126.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| F6I35_RS01605 (F6I35_0001605) | comGG | 268562..268888 (+) | 327 | WP_257360478.1 | competence type IV pilus minor pilin ComGG | - |
| F6I35_RS01610 (F6I35_0001610) | comYH | 268960..269913 (+) | 954 | WP_024053125.1 | class I SAM-dependent methyltransferase | Machinery gene |
| F6I35_RS01615 (F6I35_0001615) | - | 269960..271159 (+) | 1200 | WP_024053124.1 | acetate kinase | - |
| F6I35_RS01620 (F6I35_0001620) | glmS | 271554..273368 (+) | 1815 | WP_024053123.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| F6I35_RS01625 (F6I35_0001625) | - | 273604..275358 (+) | 1755 | WP_024053122.1 | PTS mannitol-specific transporter subunit IIBC | - |
| F6I35_RS01630 (F6I35_0001630) | - | 275383..277338 (+) | 1956 | WP_024053121.1 | BglG family transcription antiterminator | - |
| F6I35_RS01635 (F6I35_0001635) | - | 277340..277777 (+) | 438 | WP_070672299.1 | PTS sugar transporter subunit IIA | - |
| F6I35_RS01640 (F6I35_0001640) | - | 278003..279139 (+) | 1137 | WP_024053119.1 | mannitol-1-phosphate 5-dehydrogenase | - |
| F6I35_RS01645 (F6I35_0001645) | - | 279395..280331 (+) | 937 | Protein_291 | IS30 family transposase | - |
Sequence
Protein
Download Length: 97 a.a. Molecular weight: 10836.84 Da Isoelectric Point: 10.6170
>NTDB_id=888935 F6I35_RS01595 WP_024053127.1 267867..268160(+) (comGE/cglE) [Streptococcus anginosus strain UMB8616]
MGNLRKQHVKGTILLEALLALAVFVTIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGKELILGVQGK
MGNLRKQHVKGTILLEALLALAVFVTIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGKELILGVQGK
Nucleotide
Download Length: 294 bp
>NTDB_id=888935 F6I35_RS01595 WP_024053127.1 267867..268160(+) (comGE/cglE) [Streptococcus anginosus strain UMB8616]
ATGGGAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGTGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA
ATGGGAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGTGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGE/cglE | Streptococcus pneumoniae Rx1 |
50.526 |
97.938 |
0.495 |
| comGE/cglE | Streptococcus pneumoniae D39 |
50.526 |
97.938 |
0.495 |
| comGE/cglE | Streptococcus pneumoniae R6 |
50.526 |
97.938 |
0.495 |
| comGE/cglE | Streptococcus pneumoniae TIGR4 |
50.526 |
97.938 |
0.495 |
| comGE/cglE | Streptococcus mitis NCTC 12261 |
49.474 |
97.938 |
0.485 |
| comGE/cglE | Streptococcus mitis SK321 |
49.474 |
97.938 |
0.485 |
| comYE | Streptococcus mutans UA140 |
45.455 |
100 |
0.464 |
| comYE | Streptococcus mutans UA159 |
45.455 |
100 |
0.464 |