Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RS401_RS06050 Genome accession   NZ_CP135601
Coordinates   1157250..1157933 (+) Length   227 a.a.
NCBI ID   WP_000350720.1    Uniprot ID   A0A0J1I2I3
Organism   Bacillus sp. SI2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152250..1162933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RS401_RS06030 (RS401_06030) - 1153334..1154980 (+) 1647 WP_001988495.1 peptide ABC transporter substrate-binding protein -
  RS401_RS06035 (RS401_06035) - 1155008..1155211 (-) 204 WP_000559980.1 hypothetical protein -
  RS401_RS06040 (RS401_06040) spx 1155804..1156199 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  RS401_RS06045 (RS401_06045) - 1156249..1156923 (-) 675 WP_000362609.1 TerC family protein -
  RS401_RS06050 (RS401_06050) mecA 1157250..1157933 (+) 684 WP_000350720.1 adaptor protein MecA Regulator
  RS401_RS06055 (RS401_06055) - 1158006..1159550 (+) 1545 WP_000799201.1 cardiolipin synthase -
  RS401_RS06060 (RS401_06060) - 1159632..1160876 (+) 1245 WP_000612270.1 competence protein CoiA -
  RS401_RS06065 (RS401_06065) pepF 1160927..1162753 (+) 1827 WP_000003393.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26994.06 Da        Isoelectric Point: 3.9822

>NTDB_id=887105 RS401_RS06050 WP_000350720.1 1157250..1157933(+) (mecA) [Bacillus sp. SI2]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQVGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=887105 RS401_RS06050 WP_000350720.1 1157250..1157933(+) (mecA) [Bacillus sp. SI2]
TTGGATATTGAAAGAATTAATGATCATACGATGAAGTTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGTAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0J1I2I3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

55.702

100

0.559