Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RSK81_RS09670 Genome accession   NZ_CP135591
Coordinates   1958424..1959113 (-) Length   229 a.a.
NCBI ID   WP_002913166.1    Uniprot ID   -
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1953424..1964113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS09655 (RSK81_09655) nrdR 1954468..1954941 (-) 474 WP_002894570.1 transcriptional regulator NrdR -
  RSK81_RS09660 (RSK81_09660) - 1955111..1955926 (-) 816 WP_002916904.1 endonuclease/exonuclease/phosphatase family protein -
  RSK81_RS09665 (RSK81_09665) - 1955944..1958136 (-) 2193 WP_002916902.1 PTS transporter subunit IIBC -
  RSK81_RS09670 (RSK81_09670) covR 1958424..1959113 (-) 690 WP_002913166.1 DNA-binding response regulator Regulator
  RSK81_RS09675 (RSK81_09675) gndA 1959123..1960547 (-) 1425 WP_002916901.1 NADP-dependent phosphogluconate dehydrogenase -
  RSK81_RS09680 (RSK81_09680) - 1960733..1960947 (-) 215 Protein_1899 DNA cytosine methyltransferase -
  RSK81_RS09685 (RSK81_09685) - 1961055..1961900 (-) 846 WP_002916898.1 DNA adenine methylase -
  RSK81_RS09690 (RSK81_09690) - 1961903..1963642 (-) 1740 WP_315686653.1 ATP-dependent nuclease -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26295.35 Da        Isoelectric Point: 5.4408

>NTDB_id=887044 RSK81_RS09670 WP_002913166.1 1958424..1959113(-) (covR) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MAKRILLVENEKNLARFVSLELQKESFLVDLAETGQEGLALAKDVDYDLLLINYDLQDMTASGFAKQLSLIKPASVIIVL
ASREEIAEQQEAIQHFAVSYVVKPFIISDLVERVSIIFRGRDFIDQHCSLLKIPTSYRNLRVDIKNHTVYRGEEVIALTR
REYDLLVTLMGSNKVMSREQLLERVWKYESATETNVVDVYIRYLRSKIDVEGQPSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=887044 RSK81_RS09670 WP_002913166.1 1958424..1959113(-) (covR) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGGCAAAGCGAATTTTACTAGTAGAAAATGAAAAAAATCTTGCCCGATTTGTGAGTTTGGAACTGCAAAAGGAAAGCTT
TCTTGTAGATTTGGCTGAGACTGGTCAAGAGGGACTGGCTCTGGCTAAAGATGTGGATTATGACTTGCTCTTGATCAACT
ACGATCTTCAAGATATGACTGCCAGCGGTTTTGCTAAGCAGTTGAGCTTGATTAAGCCAGCGTCCGTCATTATCGTTCTG
GCTAGTCGCGAAGAGATTGCAGAGCAGCAGGAAGCAATCCAGCATTTTGCCGTTTCCTACGTAGTCAAGCCTTTCATTAT
CAGTGATTTAGTGGAGCGTGTCTCTATCATTTTCCGCGGGCGCGACTTTATCGACCAGCACTGCAGCCTCTTGAAAATTC
CGACCTCTTACAGGAATCTGCGAGTAGATATTAAAAATCATACGGTTTACCGCGGTGAGGAAGTTATTGCACTGACGCGA
CGGGAGTACGATCTGCTGGTAACCCTGATGGGCAGCAATAAGGTCATGAGCCGTGAGCAGCTGCTGGAGCGTGTCTGGAA
GTACGAGAGTGCAACGGAGACCAACGTTGTAGATGTTTATATTCGTTATCTGCGCAGTAAAATTGATGTGGAAGGGCAGC
CAAGCTATATCAAAACCGTTCGCGGTGTTGGTTATGCCATGCAGGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.598

100

0.476