Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RRU92_RS05165 Genome accession   NZ_CP135436
Coordinates   1044404..1045093 (+) Length   229 a.a.
NCBI ID   WP_049510160.1    Uniprot ID   A0A1F0A0F3
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1039404..1050093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS05140 (RRU92_05140) gpsB 1039448..1039777 (+) 330 WP_315640868.1 cell division regulator GpsB -
  RRU92_RS05150 (RRU92_05150) - 1040258..1041415 (+) 1158 WP_315640871.1 class I SAM-dependent RNA methyltransferase -
  RRU92_RS05155 (RRU92_05155) - 1041428..1042891 (+) 1464 WP_315640873.1 cell division site-positioning protein MapZ family protein -
  RRU92_RS05160 (RRU92_05160) gndA 1042968..1044392 (+) 1425 WP_315640874.1 NADP-dependent phosphogluconate dehydrogenase -
  RRU92_RS05165 (RRU92_05165) covR 1044404..1045093 (+) 690 WP_049510160.1 DNA-binding response regulator Regulator
  RRU92_RS05170 (RRU92_05170) mvk 1045300..1046178 (+) 879 WP_315640876.1 mevalonate kinase -
  RRU92_RS05175 (RRU92_05175) mvaD 1046160..1047113 (+) 954 WP_315640877.1 diphosphomevalonate decarboxylase -
  RRU92_RS05180 (RRU92_05180) - 1047100..1048113 (+) 1014 WP_315640878.1 phosphomevalonate kinase -
  RRU92_RS05185 (RRU92_05185) fni 1048091..1049092 (+) 1002 WP_315640879.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  RRU92_RS05190 (RRU92_05190) liaF 1049187..1049885 (+) 699 WP_315640880.1 cell wall-active antibiotics response protein LiaF -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26765.87 Da        Isoelectric Point: 7.0639

>NTDB_id=886542 RRU92_RS05165 WP_049510160.1 1044404..1045093(+) (covR) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPAAVIMVL
DHREELQDQLETIQRFAVSYIYKPIIIDDLVSRISAIFRGRDFIDQHCSQMKVPTAYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=886542 RRU92_RS05165 WP_049510160.1 1044404..1045093(+) (covR) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTAGAAGAGGGACAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTACTGAATG
CTCATCTAGGGGATATGACAGCCCAGGATTTTGCAGATAAGTTGAGTCGAACCAAGCCAGCTGCGGTGATCATGGTCTTG
GACCATCGAGAAGAATTGCAAGACCAACTTGAAACAATCCAGCGTTTCGCTGTTTCATACATCTATAAACCAATCATTAT
CGATGATTTGGTCAGTCGTATTTCAGCTATCTTCCGAGGTCGAGATTTCATCGACCAACACTGTAGTCAGATGAAAGTTC
CGACAGCCTATCGCAATCTGCGTATGGACGTAGAACATCATACCGTCTATCGTGGCGAGGAAATGATTGCCCTGACTCGG
CGTGAATATGATCTTTTGGCTACCCTTATGGGAAGTAAGAAGGTTTTAACTCGAGAGCAATTGCTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAAACCAATATTGTGGATGTTTATATCCGTTATCTACGTAGCAAACTTGACGTGAAAGGTCAAA
AGAGCTACATTAAAACCGTGCGTGGTGTTGGTTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1F0A0F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454