Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RMQ62_RS08210 Genome accession   NZ_CP135065
Coordinates   1696072..1696761 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain ID24665     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1691072..1701761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS08185 (RMQ62_08185) - 1691401..1692744 (+) 1344 WP_024406634.1 DEAD/DEAH box helicase -
  RMQ62_RS08190 (RMQ62_08190) - 1692762..1692986 (+) 225 WP_002936682.1 DUF4059 family protein -
  RMQ62_RS08195 (RMQ62_08195) trxB 1693000..1693917 (+) 918 WP_257047897.1 thioredoxin-disulfide reductase -
  RMQ62_RS08200 (RMQ62_08200) - 1693927..1694466 (+) 540 WP_014736258.1 DUF177 domain-containing protein -
  RMQ62_RS08205 (RMQ62_08205) gndA 1694563..1695990 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  RMQ62_RS08210 (RMQ62_08210) covR 1696072..1696761 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  RMQ62_RS08215 (RMQ62_08215) - 1697008..1698138 (+) 1131 WP_012027644.1 AI-2E family transporter -
  RMQ62_RS08220 (RMQ62_08220) nrdR 1698210..1698701 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  RMQ62_RS08225 (RMQ62_08225) - 1698688..1699839 (+) 1152 WP_313741777.1 replication initiation/membrane attachment protein -
  RMQ62_RS08230 (RMQ62_08230) dnaI 1699839..1700738 (+) 900 WP_205026995.1 primosomal protein DnaI -
  RMQ62_RS08235 (RMQ62_08235) - 1700735..1701448 (+) 714 WP_313741778.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=884743 RMQ62_RS08210 WP_012027645.1 1696072..1696761(+) (covR) [Streptococcus suis strain ID24665]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=884743 RMQ62_RS08210 WP_012027645.1 1696072..1696761(+) (covR) [Streptococcus suis strain ID24665]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGT
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432