Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   RMQ62_RS00945 Genome accession   NZ_CP135065
Coordinates   193458..194684 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain ID24665     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 188458..199684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS00915 (RMQ62_00915) - 189578..189913 (+) 336 WP_253222043.1 hypothetical protein -
  RMQ62_RS00920 (RMQ62_00920) - 190005..190964 (+) 960 WP_105095074.1 ROK family glucokinase -
  RMQ62_RS00925 (RMQ62_00925) - 191090..191368 (+) 279 WP_024381822.1 hypothetical protein -
  RMQ62_RS00930 (RMQ62_00930) - 191386..191682 (+) 297 WP_238597357.1 hypothetical protein -
  RMQ62_RS00935 (RMQ62_00935) - 191734..192573 (+) 840 WP_105095072.1 thymidylate synthase -
  RMQ62_RS00940 (RMQ62_00940) - 192748..193260 (+) 513 WP_105095071.1 dihydrofolate reductase -
  RMQ62_RS00945 (RMQ62_00945) clpX 193458..194684 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  RMQ62_RS00950 (RMQ62_00950) yihA 194738..195325 (+) 588 WP_014637952.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  RMQ62_RS00955 (RMQ62_00955) ndk 195348..195761 (+) 414 WP_002934976.1 nucleoside-diphosphate kinase -
  RMQ62_RS00960 (RMQ62_00960) lepA 195999..197831 (+) 1833 WP_024385201.1 translation elongation factor 4 -
  RMQ62_RS00965 (RMQ62_00965) - 197880..198062 (-) 183 WP_044762151.1 4-oxalocrotonate tautomerase -
  RMQ62_RS00970 (RMQ62_00970) - 198197..199510 (+) 1314 WP_167787238.1 excalibur calcium-binding domain-containing protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=884704 RMQ62_RS00945 WP_002934974.1 193458..194684(+) (clpX) [Streptococcus suis strain ID24665]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=884704 RMQ62_RS00945 WP_002934974.1 193458..194684(+) (clpX) [Streptococcus suis strain ID24665]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATTGC
AGGAAACAATGTTTTCATTTGTAATGAATGTGTAGAATTGGCCCAAGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCACAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAAGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCAAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574