Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RMQ63_RS03285 Genome accession   NZ_CP135063
Coordinates   684783..685472 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain ID32563     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 679783..690472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ63_RS03260 (RMQ63_03260) - 680254..680966 (-) 713 Protein_647 NADPH-dependent oxidoreductase -
  RMQ63_RS03265 (RMQ63_03265) dnaI 680963..681862 (-) 900 WP_044684120.1 primosomal protein DnaI -
  RMQ63_RS03270 (RMQ63_03270) - 681862..683013 (-) 1152 WP_313681117.1 replication initiation/membrane attachment protein -
  RMQ63_RS03275 (RMQ63_03275) nrdR 683000..683491 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  RMQ63_RS03280 (RMQ63_03280) - 683563..684693 (-) 1131 WP_024390116.1 AI-2E family transporter -
  RMQ63_RS03285 (RMQ63_03285) covR 684783..685472 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  RMQ63_RS03290 (RMQ63_03290) gndA 685554..686981 (-) 1428 WP_024380514.1 NADP-dependent phosphogluconate dehydrogenase -
  RMQ63_RS03295 (RMQ63_03295) - 687078..687617 (-) 540 WP_136628610.1 DUF177 domain-containing protein -
  RMQ63_RS03300 (RMQ63_03300) trxB 687627..688544 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  RMQ63_RS03305 (RMQ63_03305) - 688558..688782 (-) 225 WP_002936682.1 DUF4059 family protein -
  RMQ63_RS03310 (RMQ63_03310) - 688800..690143 (-) 1344 WP_074391721.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=884667 RMQ63_RS03285 WP_012027645.1 684783..685472(-) (covR) [Streptococcus suis strain ID32563]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=884667 RMQ63_RS03285 WP_012027645.1 684783..685472(-) (covR) [Streptococcus suis strain ID32563]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATCTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGATAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432