Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OSC47_RS01155 Genome accession   NZ_CP151161
Coordinates   219710..220366 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 20220828076     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 214710..225366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OSC47_RS01120 (OSC47_01120) dcyD 215590..216576 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  OSC47_RS01125 (OSC47_01125) tcyL 216591..217259 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  OSC47_RS01130 (OSC47_01130) tcyN 217256..218008 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  OSC47_RS01135 (OSC47_01135) sdiA 218238..218960 (+) 723 WP_001154268.1 transcriptional regulator SdiA -
  OSC47_RS01140 (OSC47_01140) yecF 219027..219251 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  OSC47_RS01145 (OSC47_01145) yecU 219238..219414 (-) 177 WP_001307856.1 protein YecU -
  OSC47_RS01150 (OSC47_01150) - 219497..219568 (-) 72 Protein_224 transcriptional regulator -
  OSC47_RS01155 (OSC47_01155) letA 219710..220366 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  OSC47_RS01160 (OSC47_01160) uvrC 220363..222195 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  OSC47_RS01165 (OSC47_01165) pgsA 222252..222800 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  OSC47_RS01185 (OSC47_01185) yecA 223449..224114 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=884579 OSC47_RS01155 WP_000611335.1 219710..220366(+) (letA) [Escherichia coli strain 20220828076]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=884579 OSC47_RS01155 WP_000611335.1 219710..220366(+) (letA) [Escherichia coli strain 20220828076]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486