Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   RND68_RS12260 Genome accession   NZ_CP134882
Coordinates   2398347..2398916 (-) Length   189 a.a.
NCBI ID   WP_000872867.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 10-5-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2393347..2403916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RND68_RS12220 (RND68_12220) - 2393821..2394429 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  RND68_RS12225 (RND68_12225) rplL 2394604..2394972 (-) 369 WP_001273587.1 50S ribosomal protein L7/L12 -
  RND68_RS12230 (RND68_12230) rplJ 2395015..2395515 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  RND68_RS12235 (RND68_12235) rplA 2395790..2396479 (-) 690 WP_001074620.1 50S ribosomal protein L1 -
  RND68_RS12240 (RND68_12240) rplK 2396687..2397109 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  RND68_RS12245 (RND68_12245) nusG 2397290..2397838 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  RND68_RS12250 (RND68_12250) secE 2397851..2398033 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  RND68_RS12255 (RND68_12255) rpmG 2398089..2398232 (-) 144 WP_001791441.1 50S ribosomal protein L33 -
  RND68_RS12260 (RND68_12260) sigH 2398347..2398916 (-) 570 WP_000872867.1 sigma-70 family RNA polymerase sigma factor Regulator
  RND68_RS12265 (RND68_12265) - 2398997..2399521 (-) 525 WP_000664740.1 NYN domain-containing protein -
  RND68_RS12270 (RND68_12270) rlmB 2399521..2400267 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  RND68_RS12275 (RND68_12275) - 2400275..2400679 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  RND68_RS12280 (RND68_12280) cysS 2400672..2402072 (-) 1401 WP_000631982.1 cysteine--tRNA ligase -
  RND68_RS12285 (RND68_12285) cysE 2402056..2402703 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23111.98 Da        Isoelectric Point: 9.6015

>NTDB_id=884324 RND68_RS12260 WP_000872867.1 2398347..2398916(-) (sigH) [Staphylococcus aureus strain 10-5-1]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSAEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=884324 RND68_RS12260 WP_000872867.1 2398347..2398916(-) (sigH) [Staphylococcus aureus strain 10-5-1]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATACGGCGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGATTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGCAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979