Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AACG41_RS10275 Genome accession   NZ_CP151067
Coordinates   2113713..2114369 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 21KM1392     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2108713..2119369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACG41_RS10245 dcyD 2109592..2110578 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  AACG41_RS10250 tcyL 2110593..2111261 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AACG41_RS10255 tcyN 2111258..2112010 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AACG41_RS10260 sdiA 2112240..2112962 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  AACG41_RS10265 yecF 2113030..2113254 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AACG41_RS10270 yecU 2113241..2113417 (-) 177 WP_001307856.1 protein YecU -
  AACG41_RS10275 letA 2113713..2114369 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AACG41_RS10280 uvrC 2114366..2116198 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AACG41_RS10285 pgsA 2116255..2116803 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AACG41_RS10305 - 2117387..2118403 (-) 1017 WP_021560873.1 tyrosine-type recombinase/integrase -
  AACG41_RS10310 - 2118372..2118635 (-) 264 WP_021560872.1 DUF4224 domain-containing protein -
  AACG41_RS10315 - 2118845..2119027 (-) 183 WP_000916333.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=883226 AACG41_RS10275 WP_000611328.1 2113713..2114369(+) (letA) [Escherichia coli strain 21KM1392]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=883226 AACG41_RS10275 WP_000611328.1 2113713..2114369(+) (letA) [Escherichia coli strain 21KM1392]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482