Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AACG43_RS09995 Genome accession   NZ_CP151063
Coordinates   2085733..2086389 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 20KM2762     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2080733..2091389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACG43_RS09960 dcyD 2081612..2082598 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  AACG43_RS09965 tcyL 2082613..2083281 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AACG43_RS09970 tcyN 2083278..2084030 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AACG43_RS09975 sdiA 2084260..2084982 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  AACG43_RS09980 yecF 2085050..2085274 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AACG43_RS09985 yecU 2085261..2085437 (-) 177 WP_000590347.1 protein YecU -
  AACG43_RS09990 - 2085520..2085591 (-) 72 Protein_1952 transcriptional regulator -
  AACG43_RS09995 letA 2085733..2086389 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AACG43_RS10000 uvrC 2086386..2088218 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AACG43_RS10005 pgsA 2088275..2088823 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AACG43_RS10025 yecA 2089473..2090138 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=883144 AACG43_RS09995 WP_000611335.1 2085733..2086389(+) (letA) [Escherichia coli strain 20KM2762]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=883144 AACG43_RS09995 WP_000611335.1 2085733..2086389(+) (letA) [Escherichia coli strain 20KM2762]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486