Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AACG39_RS09980 Genome accession   NZ_CP151059
Coordinates   2085199..2085855 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 20KM2300     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2080199..2090855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACG39_RS09945 dcyD 2081078..2082064 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  AACG39_RS09950 tcyL 2082079..2082747 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AACG39_RS09955 tcyN 2082744..2083496 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AACG39_RS09960 sdiA 2083726..2084448 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  AACG39_RS09965 yecF 2084516..2084740 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AACG39_RS09970 yecU 2084727..2084903 (-) 177 WP_000590347.1 protein YecU -
  AACG39_RS09975 - 2084986..2085057 (-) 72 Protein_1952 transcriptional regulator -
  AACG39_RS09980 letA 2085199..2085855 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AACG39_RS09985 uvrC 2085852..2087684 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AACG39_RS09990 pgsA 2087741..2088289 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AACG39_RS10010 yecA 2088939..2089604 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=883062 AACG39_RS09980 WP_000611335.1 2085199..2085855(+) (letA) [Escherichia coli strain 20KM2300]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=883062 AACG39_RS09980 WP_000611335.1 2085199..2085855(+) (letA) [Escherichia coli strain 20KM2300]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486