Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AACG47_RS10345 Genome accession   NZ_CP151050
Coordinates   2125514..2126170 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 20KM2222     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120514..2131170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACG47_RS10310 dcyD 2121393..2122379 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  AACG47_RS10315 tcyL 2122394..2123062 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AACG47_RS10320 tcyN 2123059..2123811 (+) 753 WP_001272990.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AACG47_RS10325 sdiA 2124041..2124763 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  AACG47_RS10330 yecF 2124831..2125055 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AACG47_RS10335 yecU 2125042..2125218 (-) 177 WP_001302050.1 protein YecU -
  AACG47_RS10340 - 2125256..2125372 (-) 117 WP_001302039.1 hypothetical protein -
  AACG47_RS10345 letA 2125514..2126170 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AACG47_RS10350 uvrC 2126167..2127999 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AACG47_RS10355 pgsA 2128056..2128604 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AACG47_RS10375 yecA 2129254..2129919 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=882900 AACG47_RS10345 WP_000611328.1 2125514..2126170(+) (letA) [Escherichia coli strain 20KM2222]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=882900 AACG47_RS10345 WP_000611328.1 2125514..2126170(+) (letA) [Escherichia coli strain 20KM2222]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482