Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AACG45_RS12330 Genome accession   NZ_CP151038
Coordinates   2516828..2517484 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 19KM2326N     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2511828..2522484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACG45_RS12295 dcyD 2512708..2513694 (+) 987 WP_069914858.1 D-cysteine desulfhydrase -
  AACG45_RS12300 tcyL 2513709..2514377 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AACG45_RS12305 tcyN 2514374..2515126 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AACG45_RS12310 sdiA 2515356..2516078 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  AACG45_RS12315 yecF 2516145..2516369 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AACG45_RS12320 yecU 2516356..2516532 (-) 177 WP_000590347.1 protein YecU -
  AACG45_RS12325 - 2516615..2516686 (-) 72 Protein_2390 transcriptional regulator -
  AACG45_RS12330 letA 2516828..2517484 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AACG45_RS12335 uvrC 2517481..2519313 (+) 1833 WP_073514732.1 excinuclease ABC subunit UvrC Machinery gene
  AACG45_RS12340 pgsA 2519370..2519918 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AACG45_RS12360 yecA 2520568..2521233 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=882679 AACG45_RS12330 WP_000611335.1 2516828..2517484(+) (letA) [Escherichia coli strain 19KM2326N]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=882679 AACG45_RS12330 WP_000611335.1 2516828..2517484(+) (letA) [Escherichia coli strain 19KM2326N]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486