Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   RL452_RS12985 Genome accession   NZ_CP134620
Coordinates   2607735..2608400 (-) Length   221 a.a.
NCBI ID   WP_000697879.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Sa9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2602735..2613400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL452_RS12965 (RL452_12955) - 2603205..2603318 (-) 114 WP_078062686.1 hypothetical protein -
  RL452_RS12970 (RL452_12960) - 2603977..2605977 (-) 2001 WP_338595881.1 ABC transporter permease -
  RL452_RS12975 (RL452_12965) - 2605974..2606729 (-) 756 WP_000923773.1 ABC transporter ATP-binding protein -
  RL452_RS12980 (RL452_12970) braS 2606837..2607724 (-) 888 WP_000143421.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  RL452_RS12985 (RL452_12975) braR 2607735..2608400 (-) 666 WP_000697879.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  RL452_RS12990 (RL452_12980) - 2608426..2608626 (-) 201 WP_000604725.1 hypothetical protein -
  RL452_RS12995 (RL452_12985) - 2608824..2610248 (+) 1425 WP_000953751.1 alkaline phosphatase -
  RL452_RS13000 (RL452_12990) - 2610318..2610428 (+) 111 WP_001791296.1 hypothetical protein -
  RL452_RS13005 (RL452_12995) - 2610531..2610986 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  RL452_RS13010 (RL452_13000) - 2611231..2611992 (-) 762 WP_000323448.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25388.46 Da        Isoelectric Point: 4.7961

>NTDB_id=882460 RL452_RS12985 WP_000697879.1 2607735..2608400(-) (braR) [Staphylococcus aureus strain Sa9]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=882460 RL452_RS12985 WP_000697879.1 2607735..2608400(-) (braR) [Staphylococcus aureus strain Sa9]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995