Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B0E36_RS14915 Genome accession   NZ_CP150879
Coordinates   3486856..3487530 (-) Length   224 a.a.
NCBI ID   WP_006141950.1    Uniprot ID   A0A1G7R735
Organism   Streptomyces sp. MH191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3481856..3492530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B0E36_RS14895 - 3482339..3483283 (+) 945 WP_167794003.1 diacylglycerol kinase -
  B0E36_RS14900 - 3483342..3484565 (-) 1224 WP_167794002.1 cytochrome P450 -
  B0E36_RS14905 - 3484662..3485354 (-) 693 WP_191890404.1 response regulator transcription factor -
  B0E36_RS14910 - 3485351..3486715 (-) 1365 WP_234527463.1 histidine kinase -
  B0E36_RS14915 vraR 3486856..3487530 (-) 675 WP_006141950.1 response regulator transcription factor Regulator
  B0E36_RS14920 - 3487527..3489044 (-) 1518 WP_234527464.1 sensor histidine kinase -
  B0E36_RS14925 - 3489037..3490266 (-) 1230 WP_213088052.1 acyltransferase -
  B0E36_RS14930 - 3490310..3491467 (-) 1158 WP_234527474.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24163.83 Da        Isoelectric Point: 4.8447

>NTDB_id=880965 B0E36_RS14915 WP_006141950.1 3486856..3487530(-) (vraR) [Streptomyces sp. MH191]
MTSSTIRVMIADDQVMVRQGFTVLLNAQPDIEVVGQAVDGLDAVEKAAELAPDVVLMDIRMPRLGGIDATERVIRSAPDT
KVLVLTTFDLDEYVYDALRAGASGFLLKDASAEQLAEAVRVVAAGDGLLAPGVTRRLITEFTRMRSGPRSPLKERVGTLT
ERETEVLALIAQGLSNAEIAERLCVAEQTVKTHVGRILVKLGLRDRTQAAVYAFESGVVRPSGY

Nucleotide


Download         Length: 675 bp        

>NTDB_id=880965 B0E36_RS14915 WP_006141950.1 3486856..3487530(-) (vraR) [Streptomyces sp. MH191]
ATGACGAGCAGCACGATCCGGGTCATGATCGCCGACGATCAGGTCATGGTGCGCCAGGGCTTCACGGTGCTGCTCAACGC
CCAGCCCGACATCGAGGTCGTCGGCCAGGCGGTGGACGGTCTGGACGCGGTGGAGAAGGCCGCCGAACTCGCCCCGGACG
TCGTCCTGATGGACATCCGCATGCCCCGGCTCGGCGGCATCGACGCCACCGAGCGCGTCATCCGCTCCGCGCCCGACACC
AAGGTGCTGGTGCTCACCACCTTCGACCTCGACGAGTACGTGTACGACGCGCTGCGCGCCGGCGCCTCCGGGTTCCTCCT
CAAGGACGCCTCCGCCGAGCAACTGGCGGAGGCGGTAAGGGTGGTGGCGGCGGGCGACGGACTGCTGGCGCCGGGCGTCA
CGCGGCGGCTCATCACCGAGTTCACCCGCATGCGGTCGGGGCCCCGCAGTCCGCTGAAGGAGCGCGTGGGCACACTGACC
GAGCGGGAGACGGAGGTCCTCGCGCTGATCGCGCAGGGGCTGTCCAACGCGGAGATCGCCGAGCGGCTCTGCGTGGCCGA
GCAGACGGTGAAGACCCACGTGGGCCGCATCCTGGTGAAGCTCGGCCTGCGCGACCGCACGCAGGCGGCGGTCTACGCCT
TCGAGTCGGGGGTCGTCCGCCCCTCCGGCTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-120)

Bacterial regulatory proteins, luxR family (GerE)

(158-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1G7R735

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.444

96.429

0.429
  degU Bacillus subtilis subsp. subtilis str. 168

40

100

0.402