Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   B0E36_RS14130 Genome accession   NZ_CP150879
Coordinates   3306472..3307596 (+) Length   374 a.a.
NCBI ID   WP_191852563.1    Uniprot ID   -
Organism   Streptomyces sp. MH191     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3301472..3312596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B0E36_RS14115 - 3302121..3302990 (+) 870 WP_093597092.1 hypothetical protein -
  B0E36_RS14120 - 3303029..3304753 (-) 1725 WP_349411128.1 hypothetical protein -
  B0E36_RS14125 radA/sms 3304982..3306391 (+) 1410 WP_006142123.1 DNA repair protein RadA Machinery gene
  B0E36_RS14130 disA 3306472..3307596 (+) 1125 WP_191852563.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  B0E36_RS14135 - 3307654..3308499 (-) 846 WP_191891914.1 hypothetical protein -
  B0E36_RS14140 - 3308734..3309720 (+) 987 WP_006142120.1 A/G-specific adenine glycosylase -
  B0E36_RS14145 - 3310096..3310641 (+) 546 WP_040896231.1 SigE family RNA polymerase sigma factor -
  B0E36_RS14150 - 3310629..3311345 (+) 717 WP_206316041.1 hypothetical protein -
  B0E36_RS14155 cseB 3311484..3312185 (+) 702 WP_006142116.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40071.78 Da        Isoelectric Point: 5.0058

>NTDB_id=880958 B0E36_RS14130 WP_191852563.1 3306472..3307596(+) (disA) [Streptomyces sp. MH191]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVKYPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDALSHAELLELSTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=880958 B0E36_RS14130 WP_191852563.1 3306472..3307596(+) (disA) [Streptomyces sp. MH191]
GTGGCAGCCAACGACCGGGCGGCAGCTCCCGGAAAATCCGGTGGGAGTTCCGGTGCCGACGGCCTGATGCGCGCCTCCCT
GAGCGCCGTGGCGCCCGGTACGGCCCTGCGCGACGGACTGGAGCGGGTGCTCCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTCCGACAGGACCGTGGAGTCGATGTGCACGGGCGGCTTCGTCCTCGACGTCGAGTTCACGGCGACGCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCCGACCTGTCCAAGATCCTCCGTGCGGGCGTGCAGCTGCTGCC
CGACCCGACGATCCCCACGGAGGAGACCGGCACCCGGCACCGCACCGCCGACCGGGTCAGCAAGCAGGTCAAGTACCCCG
TGGTGTCGGTCTCCCAGTCGATGCGCCTCATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCCAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTGCGCCTGGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTCGCGCAGCGCCTGGAGATGGTCCGCCGCATCG
CCACCGAGATCGCCGAGTACGTGGTCGAACTGGGCACCGACGGCCGTCTTCTCGCCCTCCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGGGAACTGGTGGTGCGGGACTACGTGCCCGAGCCCACCGCCAAGCGCTCCCGCACGGTCGACGA
GGCCCTCGCCGAGCTCGACGCGCTGAGCCACGCGGAACTGCTGGAGCTGTCCACCGTCGCCCGCGCGCTCGGCTACACCG
GCTCCCCCGAGGCGCTGGACTCCGCGGTCTCCCCGCGCGGCTTCCGCCTGCTGGCGAAGGTGCCCCGGCTGCCCGGCGCG
ATCATCGACCGTCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTGCAGACGGTGGA
CGGGGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGGCTGTCCCGGCTCGCGGAGTCCTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.983

96.524

0.444