Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B0E36_RS06535 Genome accession   NZ_CP150879
Coordinates   1563329..1563964 (-) Length   211 a.a.
NCBI ID   WP_191851957.1    Uniprot ID   A0ABZ1UWT0
Organism   Streptomyces sp. MH191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1558329..1568964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B0E36_RS06515 mmuM 1558935..1559861 (+) 927 WP_234526611.1 homocysteine S-methyltransferase -
  B0E36_RS06520 pip 1559955..1560926 (-) 972 WP_234526612.1 prolyl aminopeptidase -
  B0E36_RS06525 - 1560968..1561408 (-) 441 WP_234526614.1 hypothetical protein -
  B0E36_RS06530 - 1561493..1563184 (-) 1692 WP_234526616.1 carboxylesterase family protein -
  B0E36_RS06535 vraR 1563329..1563964 (-) 636 WP_191851957.1 response regulator transcription factor Regulator
  B0E36_RS06540 - 1564126..1564566 (+) 441 WP_167794051.1 MarR family transcriptional regulator -
  B0E36_RS06545 - 1564657..1565547 (+) 891 WP_191851958.1 NmrA/HSCARG family protein -
  B0E36_RS06550 - 1565640..1566875 (-) 1236 WP_234526618.1 sensor histidine kinase -
  B0E36_RS06555 - 1567113..1567895 (+) 783 WP_234526620.1 class I SAM-dependent methyltransferase -
  B0E36_RS06560 - 1567877..1568545 (-) 669 WP_234526622.1 ThuA domain-containing protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22343.72 Da        Isoelectric Point: 5.8765

>NTDB_id=880932 B0E36_RS06535 WP_191851957.1 1563329..1563964(-) (vraR) [Streptomyces sp. MH191]
MNPVRLLLCDDHAVVRAGLRALLSSAEGIEVVGEAGSGEEALALAPRLRPDVVLMDLQLGEGIDGVTATRELTSGAAVDP
APRVLVLTMFDTDADISRAVEAGATGYLLKAERPEELFAAIRDAAAGRAALSPPVADRLLARLRDPRPALSARESEILQQ
LSGGLGNREIARALFISEATVKTHLQRIYGKLGVETRAGAVAVAKERRLLR

Nucleotide


Download         Length: 636 bp        

>NTDB_id=880932 B0E36_RS06535 WP_191851957.1 1563329..1563964(-) (vraR) [Streptomyces sp. MH191]
GTGAACCCCGTACGCCTGCTGCTGTGCGACGACCACGCCGTGGTCAGGGCCGGACTGCGCGCCCTGCTGTCCAGCGCCGA
GGGCATCGAGGTGGTCGGCGAGGCGGGCAGCGGCGAGGAGGCGCTCGCGCTCGCCCCGCGGCTGCGGCCCGACGTCGTCC
TGATGGACCTGCAACTCGGCGAGGGCATCGACGGCGTGACGGCGACCCGGGAACTCACCTCCGGCGCGGCGGTGGACCCG
GCACCCCGCGTCCTCGTCCTCACCATGTTCGACACGGACGCCGACATCAGCCGGGCCGTCGAGGCGGGCGCCACGGGGTA
CCTGCTCAAGGCCGAACGGCCGGAGGAGCTGTTCGCCGCGATCCGGGACGCGGCGGCCGGCCGCGCGGCGCTGTCACCGC
CGGTCGCCGACCGGCTCCTGGCCCGGCTGCGCGATCCGCGCCCCGCGCTGTCCGCACGCGAGAGCGAGATCCTTCAGCAG
TTGTCGGGCGGCCTCGGCAACCGGGAGATCGCACGGGCGCTGTTCATCAGCGAGGCCACGGTGAAGACCCATCTGCAGCG
GATCTACGGCAAGTTGGGGGTGGAGACGAGGGCGGGGGCGGTCGCGGTCGCCAAGGAGCGGCGGCTGCTGCGGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(7-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.679

100

0.389
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.36