Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WMY90_RS04585 Genome accession   NZ_CP150875
Coordinates   901624..902268 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TCI125     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 896624..907268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WMY90_RS04560 (WMY90_04560) - 898725..899723 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  WMY90_RS04565 (WMY90_04565) trmD 899725..900444 (-) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  WMY90_RS04570 (WMY90_04570) rimM 900434..900952 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  WMY90_RS04585 (WMY90_04585) vraR 901624..902268 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  WMY90_RS04590 (WMY90_04590) - 902258..903268 (-) 1011 WP_011226288.1 sensor histidine kinase -
  WMY90_RS04595 (WMY90_04595) liaF 903265..903963 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  WMY90_RS04600 (WMY90_04600) - 904218..904385 (-) 168 WP_232089277.1 ion channel -
  WMY90_RS04605 (WMY90_04605) stkP/pknB 905022..906893 (-) 1872 WP_002946880.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=880853 WMY90_RS04585 WP_002951384.1 901624..902268(-) (vraR) [Streptococcus thermophilus strain TCI125]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=880853 WMY90_RS04585 WP_002951384.1 901624..902268(-) (vraR) [Streptococcus thermophilus strain TCI125]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTAGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379