Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | RJW54_RS04450 | Genome accession | NZ_CP134487 |
| Coordinates | 897270..898496 (+) | Length | 408 a.a. |
| NCBI ID | WP_002934974.1 | Uniprot ID | G7SE29 |
| Organism | Streptococcus suis strain MY1C3_3B | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 880082..955128 | 897270..898496 | within | 0 |
Gene organization within MGE regions
Location: 880082..955128
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RJW54_RS04365 (RJW54_04350) | - | 880786..881895 (-) | 1110 | WP_024395110.1 | FAD-binding oxidoreductase | - |
| RJW54_RS04370 (RJW54_04355) | - | 881980..882597 (+) | 618 | WP_011922094.1 | GDSL-type esterase/lipase family protein | - |
| RJW54_RS04375 (RJW54_04360) | lepB | 882640..883182 (+) | 543 | WP_014736040.1 | signal peptidase I | - |
| RJW54_RS04380 (RJW54_04365) | - | 883231..884487 (-) | 1257 | WP_397640631.1 | ISL3 family transposase | - |
| RJW54_RS04385 (RJW54_04370) | glmS | 884794..886605 (+) | 1812 | WP_024381447.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| RJW54_RS04390 (RJW54_04375) | - | 886948..888111 (-) | 1164 | Protein_831 | IS30 family transposase | - |
| RJW54_RS04395 (RJW54_04380) | - | 888311..888685 (+) | 375 | WP_024394326.1 | DUF1149 family protein | - |
| RJW54_RS04400 (RJW54_04385) | - | 888687..889538 (+) | 852 | WP_024394325.1 | DegV family protein | - |
| RJW54_RS04405 (RJW54_04390) | dapB | 889547..890314 (+) | 768 | WP_024394324.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| RJW54_RS04410 (RJW54_04395) | - | 890311..891522 (+) | 1212 | WP_024394323.1 | CCA tRNA nucleotidyltransferase | - |
| RJW54_RS04415 (RJW54_04400) | - | 891515..893383 (+) | 1869 | WP_024394322.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| RJW54_RS04420 (RJW54_04405) | - | 893384..893719 (+) | 336 | WP_024394321.1 | hypothetical protein | - |
| RJW54_RS04425 (RJW54_04410) | - | 893815..894774 (+) | 960 | WP_024394320.1 | ROK family glucokinase | - |
| RJW54_RS04430 (RJW54_04415) | - | 894900..895178 (+) | 279 | WP_024394319.1 | hypothetical protein | - |
| RJW54_RS04435 (RJW54_04420) | - | 895190..895492 (+) | 303 | WP_024394318.1 | hypothetical protein | - |
| RJW54_RS04440 (RJW54_04425) | - | 895545..896384 (+) | 840 | WP_024394317.1 | thymidylate synthase | - |
| RJW54_RS04445 (RJW54_04430) | - | 896560..897072 (+) | 513 | WP_024394316.1 | dihydrofolate reductase | - |
| RJW54_RS04450 (RJW54_04435) | clpX | 897270..898496 (+) | 1227 | WP_002934974.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| RJW54_RS04455 (RJW54_04440) | yihA | 898552..899139 (+) | 588 | WP_014638915.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| RJW54_RS04460 (RJW54_04445) | ndk | 899162..899575 (+) | 414 | WP_024394314.1 | nucleoside-diphosphate kinase | - |
| RJW54_RS04465 (RJW54_04450) | lepA | 899671..901503 (+) | 1833 | WP_002943192.1 | translation elongation factor 4 | - |
| RJW54_RS04470 (RJW54_04455) | - | 901553..901735 (-) | 183 | WP_002934978.1 | 4-oxalocrotonate tautomerase | - |
| RJW54_RS04475 (RJW54_04460) | - | 901870..903177 (+) | 1308 | WP_002934980.1 | excalibur calcium-binding domain-containing protein | - |
| RJW54_RS04480 (RJW54_04465) | - | 903239..903463 (+) | 225 | WP_002934981.1 | hypothetical protein | - |
| RJW54_RS04485 (RJW54_04470) | - | 903562..904143 (+) | 582 | WP_002934983.1 | thymidine kinase | - |
| RJW54_RS04490 (RJW54_04475) | prfA | 904424..905503 (+) | 1080 | WP_002934984.1 | peptide chain release factor 1 | - |
| RJW54_RS04495 (RJW54_04480) | prmC | 905503..906336 (+) | 834 | WP_002934985.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| RJW54_RS04500 (RJW54_04485) | - | 906323..906931 (+) | 609 | WP_009909811.1 | L-threonylcarbamoyladenylate synthase | - |
| RJW54_RS04505 (RJW54_04490) | - | 906928..907359 (+) | 432 | WP_172015522.1 | GNAT family N-acetyltransferase | - |
| RJW54_RS04510 (RJW54_04495) | glyA | 907383..908642 (+) | 1260 | WP_002934988.1 | serine hydroxymethyltransferase | - |
| RJW54_RS04515 (RJW54_04500) | - | 908642..909616 (+) | 975 | WP_002934989.1 | nucleoid-associated protein | - |
| RJW54_RS04520 (RJW54_04505) | - | 909617..910216 (+) | 600 | WP_002934990.1 | lysozyme family protein | - |
| RJW54_RS04525 (RJW54_04510) | - | 910317..911075 (+) | 759 | WP_002934991.1 | SDR family NAD(P)-dependent oxidoreductase | - |
| RJW54_RS04530 (RJW54_04515) | - | 911092..911844 (+) | 753 | WP_002934992.1 | DUF6287 domain-containing protein | - |
| RJW54_RS04535 (RJW54_04520) | - | 911841..912173 (+) | 333 | WP_002934993.1 | HIRAN domain-containing protein | - |
| RJW54_RS04540 (RJW54_04525) | - | 912194..913141 (-) | 948 | WP_009909815.1 | hypothetical protein | - |
| RJW54_RS04545 (RJW54_04530) | - | 913169..913957 (-) | 789 | WP_002934995.1 | hypothetical protein | - |
| RJW54_RS04550 (RJW54_04535) | - | 914158..915855 (+) | 1698 | WP_024394313.1 | AAA family ATPase | - |
| RJW54_RS04555 (RJW54_04540) | mcrC | 915852..916901 (+) | 1050 | WP_002934997.1 | 5-methylcytosine-specific restriction endonuclease system specificity protein McrC | - |
| RJW54_RS04560 (RJW54_04545) | guaA | 917063..918613 (-) | 1551 | WP_002934999.1 | glutamine-hydrolyzing GMP synthase | - |
| RJW54_RS04565 (RJW54_04550) | - | 918889..919587 (+) | 699 | WP_002943214.1 | GntR family transcriptional regulator | - |
| RJW54_RS04570 (RJW54_04555) | - | 919690..920022 (+) | 333 | WP_002935001.1 | putative DNA-binding protein | - |
| RJW54_RS04575 (RJW54_04560) | ffh | 920035..921609 (+) | 1575 | WP_002935002.1 | signal recognition particle protein | - |
| RJW54_RS04580 (RJW54_04565) | - | 921803..922471 (+) | 669 | WP_002935003.1 | SatD family protein | - |
| RJW54_RS04585 (RJW54_04570) | - | 922475..923215 (+) | 741 | WP_009909823.1 | DUF3307 domain-containing protein | - |
| RJW54_RS04590 (RJW54_04575) | - | 923281..923802 (+) | 522 | WP_002935005.1 | AAA family ATPase | - |
| RJW54_RS04595 (RJW54_04580) | xerS | 923969..925039 (+) | 1071 | WP_172015521.1 | tyrosine recombinase XerS | - |
| RJW54_RS04600 (RJW54_04585) | - | 925109..926617 (-) | 1509 | WP_013730362.1 | phosphoglucomutase | - |
| RJW54_RS04605 (RJW54_04590) | - | 926693..927634 (-) | 942 | WP_002935009.1 | sensor histidine kinase | - |
| RJW54_RS04610 (RJW54_04595) | - | 927631..928296 (-) | 666 | WP_009909826.1 | response regulator transcription factor | - |
| RJW54_RS04615 (RJW54_04600) | - | 928335..928541 (-) | 207 | WP_370287028.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| RJW54_RS04620 (RJW54_04605) | relB | 928582..928821 (-) | 240 | WP_002935014.1 | type II toxin-antitoxin system RelB family antitoxin | - |
| RJW54_RS04625 (RJW54_04610) | - | 928913..930883 (-) | 1971 | WP_013730363.1 | FtsX-like permease family protein | - |
| RJW54_RS04630 (RJW54_04615) | - | 930884..931636 (-) | 753 | WP_002935019.1 | ABC transporter ATP-binding protein | - |
| RJW54_RS04635 (RJW54_04620) | - | 931772..932506 (-) | 735 | WP_011922410.1 | ABC transporter permease | - |
| RJW54_RS04640 (RJW54_04625) | - | 932508..933254 (-) | 747 | WP_011922411.1 | ABC transporter permease | - |
| RJW54_RS04645 (RJW54_04630) | - | 933256..934158 (-) | 903 | WP_011922412.1 | ABC transporter ATP-binding protein | - |
| RJW54_RS04650 (RJW54_04635) | - | 934179..934556 (-) | 378 | WP_011922413.1 | NisI/SpaI family lantibiotic immunity lipoprotein | - |
| RJW54_RS04655 (RJW54_04640) | - | 934569..934709 (-) | 141 | WP_012775106.1 | hypothetical protein | - |
| RJW54_RS04660 (RJW54_04645) | - | 934849..936015 (-) | 1167 | WP_024394863.1 | acetyl-CoA carboxylase biotin carboxylase subunit family protein | - |
| RJW54_RS04665 (RJW54_04650) | - | 936033..936758 (-) | 726 | WP_024394864.1 | esterase family protein | - |
| RJW54_RS04670 (RJW54_04655) | - | 936789..937616 (-) | 828 | WP_011922416.1 | alpha/beta hydrolase | - |
| RJW54_RS04675 (RJW54_04660) | - | 937730..938734 (-) | 1005 | WP_024394865.1 | DNA glycosylase AlkZ-like family protein | - |
| RJW54_RS04680 (RJW54_04665) | - | 938799..939634 (-) | 836 | Protein_889 | GyrI-like domain-containing protein | - |
| RJW54_RS04685 (RJW54_04670) | trmFO | 939711..941045 (-) | 1335 | WP_024394866.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| RJW54_RS04690 (RJW54_04675) | - | 941241..941992 (-) | 752 | Protein_891 | HAD family hydrolase | - |
| RJW54_RS04695 (RJW54_04680) | - | 942177..943376 (-) | 1200 | WP_029174754.1 | site-specific integrase | - |
| RJW54_RS04700 (RJW54_04685) | - | 943379..943627 (-) | 249 | WP_000860228.1 | DUF3173 family protein | - |
| RJW54_RS04705 (RJW54_04690) | - | 943897..944121 (-) | 225 | WP_003108992.1 | helix-turn-helix domain-containing protein | - |
| RJW54_RS04710 (RJW54_04695) | - | 944302..945261 (-) | 960 | WP_029178413.1 | ATP-grasp domain-containing protein | - |
| RJW54_RS04715 (RJW54_04700) | - | 945434..945808 (-) | 375 | WP_029178412.1 | hypothetical protein | - |
| RJW54_RS04720 (RJW54_04705) | - | 945829..946038 (-) | 210 | WP_029174752.1 | hypothetical protein | - |
| RJW54_RS04725 (RJW54_04710) | - | 946234..947232 (-) | 999 | WP_228475166.1 | MFS transporter | - |
| RJW54_RS04730 (RJW54_04715) | - | 947222..947806 (-) | 585 | WP_029174751.1 | ATP-grasp domain-containing protein | - |
| RJW54_RS04735 (RJW54_04720) | - | 947984..948832 (+) | 849 | WP_029174750.1 | helix-turn-helix domain-containing protein | - |
| RJW54_RS04740 (RJW54_04725) | - | 948876..950738 (-) | 1863 | WP_029174749.1 | SAG1250 family conjugative relaxase | - |
| RJW54_RS04745 (RJW54_04730) | mobC | 950725..951090 (-) | 366 | WP_012775542.1 | plasmid mobilization relaxosome protein MobC | - |
| RJW54_RS04750 (RJW54_04735) | - | 951100..951459 (-) | 360 | WP_029174748.1 | SAG1252 family conjugative relaxosome accessory protein | - |
| RJW54_RS04755 (RJW54_04740) | - | 951802..952437 (-) | 636 | WP_397640633.1 | AAA family ATPase | - |
| RJW54_RS04760 (RJW54_04745) | - | 952451..952942 (-) | 492 | WP_397640634.1 | hypothetical protein | - |
| RJW54_RS04765 (RJW54_04750) | - | 952943..953731 (-) | 789 | WP_029174746.1 | DUF6414 family protein | - |
| RJW54_RS04770 (RJW54_04755) | pezT | 953747..954514 (-) | 768 | WP_029174745.1 | type II toxin-antitoxin system toxin PezT | - |
| RJW54_RS04775 (RJW54_04760) | pezA | 954514..954990 (-) | 477 | WP_024409333.1 | type II toxin-antitoxin system antitoxin PezA | - |
Sequence
Protein
Download Length: 408 a.a. Molecular weight: 45318.84 Da Isoelectric Point: 4.6382
>NTDB_id=880264 RJW54_RS04450 WP_002934974.1 897270..898496(+) (clpX) [Streptococcus suis strain MY1C3_3B]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA
Nucleotide
Download Length: 1227 bp
>NTDB_id=880264 RJW54_RS04450 WP_002934974.1 897270..898496(+) (clpX) [Streptococcus suis strain MY1C3_3B]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
83.13 |
100 |
0.833 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.209 |
98.529 |
0.574 |