Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RJW49_RS08125 Genome accession   NZ_CP134477
Coordinates   1589750..1590439 (-) Length   229 a.a.
NCBI ID   WP_074393349.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1584750..1595439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS08100 (RJW49_08100) - 1585221..1585846 (-) 626 Protein_1557 nitroreductase family protein -
  RJW49_RS08105 (RJW49_08105) dnaI 1585930..1586829 (-) 900 WP_012027642.1 primosomal protein DnaI -
  RJW49_RS08110 (RJW49_08110) - 1586829..1587980 (-) 1152 WP_012027643.1 replication initiation/membrane attachment protein -
  RJW49_RS08115 (RJW49_08115) nrdR 1587967..1588458 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  RJW49_RS08120 (RJW49_08120) - 1588530..1589660 (-) 1131 WP_012027644.1 AI-2E family transporter -
  RJW49_RS08125 (RJW49_08125) covR 1589750..1590439 (-) 690 WP_074393349.1 DNA-binding response regulator Regulator
  RJW49_RS08130 (RJW49_08130) gndA 1590521..1591948 (-) 1428 WP_014736257.1 NADP-dependent phosphogluconate dehydrogenase -
  RJW49_RS08135 (RJW49_08135) - 1592045..1592584 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  RJW49_RS08140 (RJW49_08140) trxB 1592594..1593511 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  RJW49_RS08145 (RJW49_08145) - 1593525..1593749 (-) 225 WP_014638521.1 DUF4059 family protein -
  RJW49_RS08150 (RJW49_08150) - 1593767..1595110 (-) 1344 WP_074393348.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26239.14 Da        Isoelectric Point: 5.3968

>NTDB_id=880228 RJW49_RS08125 WP_074393349.1 1589750..1590439(-) (covR) [Streptococcus suis strain NLS40]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
IEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=880228 RJW49_RS08125 WP_074393349.1 1589750..1590439(-) (covR) [Streptococcus suis strain NLS40]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
ATTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACACGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432