Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   RJW49_RS05825 Genome accession   NZ_CP134477
Coordinates   1110034..1111260 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain NLS40     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1105034..1116260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS05795 (RJW49_05795) - 1105061..1105285 (-) 225 WP_002934981.1 hypothetical protein -
  RJW49_RS05800 (RJW49_05800) - 1105347..1106660 (-) 1314 WP_014735869.1 excalibur calcium-binding domain-containing protein -
  RJW49_RS05805 (RJW49_05805) - 1106795..1106977 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  RJW49_RS05810 (RJW49_05810) lepA 1107027..1108859 (-) 1833 WP_014735870.1 translation elongation factor 4 -
  RJW49_RS05815 (RJW49_05815) ndk 1108955..1109368 (-) 414 WP_014735871.1 nucleoside-diphosphate kinase -
  RJW49_RS05820 (RJW49_05820) yihA 1109391..1109978 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  RJW49_RS05825 (RJW49_05825) clpX 1110034..1111260 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  RJW49_RS05830 (RJW49_05830) - 1111458..1111970 (-) 513 WP_011922360.1 dihydrofolate reductase -
  RJW49_RS05835 (RJW49_05835) - 1112255..1113094 (-) 840 WP_011922359.1 thymidylate synthase -
  RJW49_RS05840 (RJW49_05840) - 1113147..1113449 (-) 303 WP_012775088.1 hypothetical protein -
  RJW49_RS05845 (RJW49_05845) - 1113461..1113739 (-) 279 WP_012775087.1 hypothetical protein -
  RJW49_RS05850 (RJW49_05850) - 1113865..1114824 (-) 960 WP_014735873.1 ROK family glucokinase -
  RJW49_RS05855 (RJW49_05855) - 1114920..1115255 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=880218 RJW49_RS05825 WP_002934974.1 1110034..1111260(-) (clpX) [Streptococcus suis strain NLS40]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=880218 RJW49_RS05825 WP_002934974.1 1110034..1111260(-) (clpX) [Streptococcus suis strain NLS40]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCAGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGTAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCTATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574