Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RJW55_RS02640 Genome accession   NZ_CP134473
Coordinates   553199..553888 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain TMW_SS028     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 548199..558888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS02615 (RJW55_02615) - 548537..549880 (+) 1344 WP_024380515.1 DEAD/DEAH box helicase -
  RJW55_RS02620 (RJW55_02620) - 549898..550122 (+) 225 WP_002936682.1 DUF4059 family protein -
  RJW55_RS02625 (RJW55_02625) trxB 550136..551053 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  RJW55_RS02630 (RJW55_02630) - 551063..551602 (+) 540 WP_024417740.1 DUF177 domain-containing protein -
  RJW55_RS02635 (RJW55_02635) gndA 551690..553117 (+) 1428 WP_043027102.1 NADP-dependent phosphogluconate dehydrogenase -
  RJW55_RS02640 (RJW55_02640) covR 553199..553888 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  RJW55_RS02645 (RJW55_02645) - 553978..555108 (+) 1131 WP_043026138.1 AI-2E family transporter -
  RJW55_RS02650 (RJW55_02650) nrdR 555180..555671 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  RJW55_RS02655 (RJW55_02655) - 555658..556809 (+) 1152 WP_043026137.1 replication initiation/membrane attachment protein -
  RJW55_RS02660 (RJW55_02660) dnaI 556809..557708 (+) 900 WP_043026135.1 primosomal protein DnaI -
  RJW55_RS02665 (RJW55_02665) - 557705..558418 (+) 714 WP_043026134.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=880154 RJW55_RS02640 WP_012027645.1 553199..553888(+) (covR) [Streptococcus suis strain TMW_SS028]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=880154 RJW55_RS02640 WP_012027645.1 553199..553888(+) (covR) [Streptococcus suis strain TMW_SS028]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTAGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432