Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OCX18_RS07995 Genome accession   NZ_AP024728
Coordinates   1653968..1654654 (-) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain 59553     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1648968..1659654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCX18_RS07975 rpsT 1649882..1650133 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OCX18_RS07980 holA 1650178..1651152 (-) 975 WP_001282568.1 DNA polymerase III subunit delta -
  OCX18_RS07985 comEC 1651209..1653410 (-) 2202 WP_172576660.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OCX18_RS07990 - 1653415..1653876 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OCX18_RS07995 comEA 1653968..1654654 (-) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  OCX18_RS08000 - 1654694..1655410 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OCX18_RS08005 rsfS 1655413..1655766 (-) 354 WP_001088022.1 ribosome silencing factor -
  OCX18_RS08010 yqeK 1655767..1656351 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OCX18_RS08015 nadD 1656341..1656910 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OCX18_RS08020 yhbY 1656913..1657203 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  OCX18_RS08025 aroE 1657207..1658013 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  OCX18_RS08030 yqeH 1658027..1659127 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=87825 OCX18_RS07995 WP_001793467.1 1653968..1654654(-) (comEA) [Staphylococcus aureus strain 59553]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=87825 OCX18_RS07995 WP_001793467.1 1653968..1654654(-) (comEA) [Staphylococcus aureus strain 59553]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment