Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   RDV49_RS09965 Genome accession   NZ_CP133988
Coordinates   2049309..2050607 (-) Length   432 a.a.
NCBI ID   WP_003010307.1    Uniprot ID   A0AAX4AX83
Organism   Streptococcus parasanguinis strain B-1756     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2044309..2055607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS09955 (RDV49_09955) hpf 2048023..2048565 (-) 543 WP_003010301.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  RDV49_RS09960 (RDV49_09960) - 2048647..2049312 (-) 666 WP_003010303.1 ComF family protein -
  RDV49_RS09965 (RDV49_09965) comFA/cflA 2049309..2050607 (-) 1299 WP_003010307.1 DEAD/DEAH box helicase Machinery gene
  RDV49_RS09970 (RDV49_09970) - 2050663..2051304 (+) 642 WP_003010310.1 YigZ family protein -
  RDV49_RS09975 (RDV49_09975) cysK 2051428..2052351 (+) 924 WP_003004014.1 cysteine synthase A -
  RDV49_RS09980 (RDV49_09980) - 2052402..2052767 (-) 366 WP_023920312.1 S1 RNA-binding domain-containing protein -
  RDV49_RS09985 (RDV49_09985) - 2052769..2054169 (-) 1401 WP_037608300.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RDV49_RS09990 (RDV49_09990) - 2054214..2054846 (-) 633 WP_003010319.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49463.60 Da        Isoelectric Point: 9.3591

>NTDB_id=878185 RDV49_RS09965 WP_003010307.1 2049309..2050607(-) (comFA/cflA) [Streptococcus parasanguinis strain B-1756]
MKIEDSYGRLLTESQMTNDLKEIAQELPAMEKQNGRYQCFRCGSLIDQKLWKLSEEVLYCRACIQLGRIRSDQKLYAIAQ
KDFEGQEVLNWKGTLTSYQQEVSEGLIQAVKAGKHALVHAVTGAGKTEMMYQVVATAIKAGKAVCIATPRIDVCIELYGR
MKEDFSCPISLLHGESEPYFRTPLVIATTHQLLKFYQAFDLLIIDEVDAFPYVDNPILYKAAQNAIKKEGNTLYLTATST
DELDKKVKKKEIIRYSLPRRFHGNPLVVPEIKWVPKIREKIEKGRIPYQLLQLIKKQIQTHYPLLIFVSEIELGQQFTEN
LKKYFPKETVGFVSSQTTDRLRMVEEFRNRAITMLVSTTILERGVTFPFVDVFVLESNHKLFTKSALVQISGRVGRSKER
PTGKLLFLSDGITREMKKAIKEIKEMNQEAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=878185 RDV49_RS09965 WP_003010307.1 2049309..2050607(-) (comFA/cflA) [Streptococcus parasanguinis strain B-1756]
ATGAAGATAGAAGATTCTTATGGAAGACTCTTAACGGAGAGTCAAATGACAAATGATCTGAAAGAAATTGCCCAAGAACT
TCCAGCTATGGAAAAACAGAATGGAAGGTACCAATGTTTTCGATGTGGCAGTTTGATTGATCAAAAACTTTGGAAGTTGA
GTGAGGAGGTGCTGTATTGTAGAGCCTGTATCCAATTGGGAAGGATCCGGAGTGATCAAAAACTTTATGCTATTGCACAG
AAGGACTTTGAAGGACAGGAGGTGTTAAACTGGAAGGGAACCTTGACTTCCTATCAACAAGAGGTATCTGAAGGACTTAT
CCAAGCAGTTAAAGCAGGAAAACATGCCTTGGTACATGCTGTGACAGGAGCTGGAAAAACAGAAATGATGTATCAGGTTG
TAGCAACAGCGATCAAGGCAGGAAAAGCAGTCTGTATTGCTACCCCAAGAATCGATGTCTGTATAGAATTGTACGGAAGA
ATGAAGGAAGATTTTTCCTGCCCCATCTCTTTGCTTCATGGAGAATCGGAACCCTATTTTAGAACACCCTTGGTGATCGC
TACAACCCACCAATTGCTAAAGTTTTATCAGGCCTTTGATCTCCTTATTATAGATGAAGTAGATGCTTTTCCCTATGTAG
ACAATCCAATCCTATATAAAGCAGCTCAGAATGCAATAAAAAAAGAGGGGAATACCCTATATTTAACAGCAACCTCTACA
GATGAGTTAGATAAAAAGGTCAAGAAAAAAGAAATCATTCGTTATAGCCTTCCAAGAAGATTTCATGGGAACCCACTAGT
GGTCCCTGAAATAAAATGGGTGCCGAAAATTAGAGAAAAAATAGAAAAAGGAAGAATCCCTTACCAACTATTGCAACTGA
TCAAGAAACAAATACAAACTCACTACCCATTGTTAATCTTTGTATCTGAAATAGAATTAGGACAACAATTTACCGAGAAC
TTAAAAAAATACTTTCCCAAAGAAACAGTAGGTTTTGTATCCTCACAGACAACAGACCGTCTACGAATGGTAGAAGAGTT
TAGAAACAGAGCCATAACCATGCTAGTCTCTACAACAATTTTAGAAAGAGGAGTGACTTTTCCGTTTGTAGATGTCTTTG
TTTTAGAAAGTAATCACAAATTATTTACTAAAAGTGCTCTCGTACAAATTTCAGGAAGGGTCGGTCGAAGTAAAGAAAGA
CCAACAGGTAAACTACTTTTTCTATCAGATGGCATAACACGAGAAATGAAGAAAGCGATCAAAGAAATAAAGGAAATGAA
TCAGGAGGCTGGATTTTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(290-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

60.508

100

0.606
  comFA/cflA Streptococcus pneumoniae D39

60.508

100

0.606
  comFA/cflA Streptococcus pneumoniae R6

60.508

100

0.606
  comFA/cflA Streptococcus mitis SK321

60.277

100

0.604
  comFA/cflA Streptococcus pneumoniae TIGR4

60.277

100

0.604
  comFA/cflA Streptococcus mitis NCTC 12261

60.046

100

0.602
  comFA Lactococcus lactis subsp. cremoris KW2

48.926

96.991

0.475
  comFA Latilactobacillus sakei subsp. sakei 23K

37.413

100

0.375