Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RIM74_RS02685 Genome accession   NZ_CP133955
Coordinates   510805..511554 (+) Length   249 a.a.
NCBI ID   WP_317582990.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain HTP133     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 505805..516554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM74_RS02660 (RIM74_02660) recX 506208..506984 (-) 777 WP_012679951.1 recombination regulator RecX -
  RIM74_RS02665 (RIM74_02665) - 507048..508016 (+) 969 WP_012679950.1 DNA-binding protein -
  RIM74_RS02670 (RIM74_02670) rlmD 508013..509380 (+) 1368 WP_012679949.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  RIM74_RS02675 (RIM74_02675) - 509701..509958 (+) 258 WP_012679948.1 Blp family class II bacteriocin -
  RIM74_RS02680 (RIM74_02680) - 509975..510178 (+) 204 WP_012679947.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  RIM74_RS02685 (RIM74_02685) comE/blpR 510805..511554 (+) 750 WP_317582990.1 response regulator transcription factor Regulator
  RIM74_RS10245 - 511554..512888 (+) 1335 WP_012679945.1 sensor histidine kinase -
  RIM74_RS02695 (RIM74_02695) - 513010..513141 (-) 132 WP_012677513.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  RIM74_RS02700 (RIM74_02700) - 513241..514599 (-) 1359 WP_012679944.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29217.70 Da        Isoelectric Point: 8.7544

>NTDB_id=877856 RIM74_RS02685 WP_317582990.1 510805..511554(+) (comE/blpR) [Streptococcus equi subsp. equi strain HTP133]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=877856 RIM74_RS02685 WP_317582990.1 510805..511554(+) (comE/blpR) [Streptococcus equi subsp. equi strain HTP133]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGAACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCAAACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACGGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386