Detailed information NTG0877767

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: RIM63_RS05570
• Genome accession: NZ_CP133952
• Coordinates: 1154619..1155848 (-)
• Length: 409 a.a.
• NCBI ID: WP_042670717.1
• Uniprot ID: A0A6M1KP89
• Organism: Streptococcus equi subsp. zooepidemicus strain HT321
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1149619..1160848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM63_RS05555 (RIM63_05555)	-	1150636..1153638 (-)	3003	WP_317583283.1	leucine-rich repeat domain-containing protein	-
RIM63_RS05560 (RIM63_05560)	-	1153724..1154005 (-)	282	WP_317583284.1	hypothetical protein	-
RIM63_RS05565 (RIM63_05565)	yihA	1154010..1154609 (-)	600	WP_317585263.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
RIM63_RS05570 (RIM63_05570)	clpX	1154619..1155848 (-)	1230	WP_042670717.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
RIM63_RS05575 (RIM63_05575)	-	1155884..1156054 (-)	171	WP_012515696.1	hypothetical protein	-
RIM63_RS05580 (RIM63_05580)	-	1156074..1156571 (-)	498	WP_037581014.1	dihydrofolate reductase	-
RIM63_RS05585 (RIM63_05585)	-	1156652..1157491 (-)	840	WP_037581013.1	thymidylate synthase	-
RIM63_RS05590 (RIM63_05590)	-	1157676..1158851 (+)	1176	WP_317583285.1	hydroxymethylglutaryl-CoA synthase	-
RIM63_RS05595 (RIM63_05595)	-	1158838..1160121 (+)	1284	WP_317585265.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45173.67 Da
• Isoelectric Point: 4.5698

>NTDB_id=877767 RIM63_RS05570 WP_042670717.1 1154619..1155848(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain HT321]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLSDLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=877767 RIM63_RS05570 WP_042670717.1 1154619..1155848(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAACAATGTCTTTATTTGTAATGAATGCGTTGCCTTGTCACAAGAAATCATCAAAGAAGAATTGGCAGAGGAGG
TTCTCTCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGTAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGCTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAGGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCCTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTGGCAGCCCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCTCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGTGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATCGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTTGAGGGT
CAATCAAAGCCCGTTTTAGAGATAGCCTAG

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A6M1KP89

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.509	100	0.885
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.352	98.044	0.582