Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHC13_RS05245 Genome accession   NZ_CP150487
Coordinates   1009402..1010046 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis strain JNF2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1004402..1015046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHC13_RS05230 (WHC13_05230) glpD 1004573..1006240 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  WHC13_RS05235 (WHC13_05235) pgcA 1006372..1008117 (+) 1746 WP_003244986.1 phosphoglucomutase -
  WHC13_RS05240 (WHC13_05240) yhcY 1008266..1009405 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  WHC13_RS05245 (WHC13_05245) vraR 1009402..1010046 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  WHC13_RS05250 (WHC13_05250) yhdA 1010043..1010567 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  WHC13_RS05255 (WHC13_05255) yhdB 1010582..1010824 (-) 243 WP_003233373.1 YhdB family protein -
  WHC13_RS05260 (WHC13_05260) yhdC 1011025..1011348 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  WHC13_RS05265 (WHC13_05265) lytF 1011390..1012856 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  WHC13_RS05270 (WHC13_05270) nsrR 1013009..1013449 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=877109 WHC13_RS05245 WP_003245647.1 1009402..1010046(+) (vraR) [Bacillus subtilis strain JNF2]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=877109 WHC13_RS05245 WP_003245647.1 1009402..1010046(+) (vraR) [Bacillus subtilis strain JNF2]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411