Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RF668_RS06230 Genome accession   NZ_CP133787
Coordinates   1196611..1197312 (+) Length   233 a.a.
NCBI ID   WP_011676802.1    Uniprot ID   A0A0M2ZUZ8
Organism   Lactococcus cremoris strain KCKM 0438     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1191611..1202312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RF668_RS06215 (RF668_06215) - 1194008..1194916 (+) 909 WP_043735641.1 diacylglycerol kinase family protein -
  RF668_RS06220 (RF668_06220) - 1195062..1195748 (+) 687 WP_043735639.1 amino acid ABC transporter permease -
  RF668_RS06225 (RF668_06225) - 1195748..1196482 (+) 735 WP_011676803.1 amino acid ABC transporter ATP-binding protein -
  RF668_RS06230 (RF668_06230) mecA 1196611..1197312 (+) 702 WP_011676802.1 adaptor protein MecA Regulator
  RF668_RS06235 (RF668_06235) - 1197315..1198640 (+) 1326 WP_011676801.1 MraY family glycosyltransferase -
  RF668_RS06240 (RF668_06240) sufC 1198816..1199586 (+) 771 WP_011835712.1 Fe-S cluster assembly ATPase SufC -
  RF668_RS06245 (RF668_06245) sufD 1199726..1200982 (+) 1257 WP_043735636.1 Fe-S cluster assembly protein SufD -
  RF668_RS06250 (RF668_06250) - 1200982..1202199 (+) 1218 WP_043735634.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27046.46 Da        Isoelectric Point: 4.1802

>NTDB_id=876880 RF668_RS06230 WP_011676802.1 1196611..1197312(+) (mecA) [Lactococcus cremoris strain KCKM 0438]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGAKKEEAEHEPDFIYYSIRYDDMMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKAKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLITTRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=876880 RF668_RS06230 WP_011676802.1 1196611..1197312(+) (mecA) [Lactococcus cremoris strain KCKM 0438]
ATGAAGTATGAGGATATAAATGAAAACACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAGTT
ATCTGACTTTTTTGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTAGTTGATGAACTTGGCTTAGAAAATCGTT
TTGGAAATGTAGGGATGTTAACTTTCCAAATTCAACCCTTCCCACAAGGCGTCCATATGATTGTTCATGAAGAAGCAATG
TTGGGTGAAGGCGGAGAGATTCCAGATGATCCTGAAGAATTTGAAGAATTAATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGACTTGGTTTACCAGGGGCTAAAAAAGAAG
AAGCCGAACATGAGCCAGACTTTATATACTACTCTATTCGTTATGATGACATGATGTCTGTCTTGACTGGAATAAAAAAT
GTGAAATTCGCAGATGAAGAGTCAGAATTTTATCGTTATGATGGTAATTTTTATCTTGTTGTTTTAGATAATCAAAAAGC
AAAAGGTAAAATGCATGTTGAAAGCACACGTTCACGGATGATGGAATATGGTGAAGCGACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGCCTAATCACAACGCGTGCCTTAGACGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M2ZUZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

100

100

1
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

96.567

100

0.966