Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WID27_RS30395 Genome accession   NZ_CP149796
Coordinates   7020028..7020672 (+) Length   214 a.a.
NCBI ID   WP_070201465.1    Uniprot ID   A0A1E7LU48
Organism   Streptomyces sp. F41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7015028..7025672
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS30375 (WID27_30375) - 7015272..7016018 (-) 747 WP_070201467.1 transglycosylase SLT domain-containing protein -
  WID27_RS30380 (WID27_30380) - 7016292..7017563 (-) 1272 WP_339153437.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  WID27_RS30385 (WID27_30385) - 7017626..7018351 (-) 726 WP_070201485.1 SDR family oxidoreductase -
  WID27_RS30390 (WID27_30390) - 7018890..7020035 (+) 1146 WP_079167307.1 GAF domain-containing sensor histidine kinase -
  WID27_RS30395 (WID27_30395) vraR 7020028..7020672 (+) 645 WP_070201465.1 response regulator transcription factor Regulator
  WID27_RS30400 (WID27_30400) - 7020806..7021057 (+) 252 WP_018488230.1 chaplin -
  WID27_RS30405 (WID27_30405) - 7021405..7022196 (-) 792 WP_070201464.1 hypothetical protein -
  WID27_RS30410 (WID27_30410) - 7022363..7023160 (+) 798 WP_070201463.1 ABC transporter ATP-binding protein -
  WID27_RS30415 (WID27_30415) - 7023306..7023734 (+) 429 WP_339153441.1 NfeD family protein -
  WID27_RS30420 (WID27_30420) - 7023850..7024869 (+) 1020 WP_019766173.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23048.28 Da        Isoelectric Point: 5.1683

>NTDB_id=875274 WID27_RS30395 WP_070201465.1 7020028..7020672(+) (vraR) [Streptomyces sp. F41]
MADKTIRVLLVDDHQVVRRGLRTFLEIQEDIEVVGEASDGAEGVARTEELRPDVVLMDIKMPGTDGIEALRRLRELENPA
KILIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLAQDDAGSGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGAAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=875274 WID27_RS30395 WP_070201465.1 7020028..7020672(+) (vraR) [Streptomyces sp. F41]
GTGGCTGACAAGACCATCAGGGTGCTGCTGGTCGACGACCACCAGGTCGTCCGCCGTGGACTGCGTACGTTCCTGGAGAT
CCAGGAGGACATCGAGGTCGTCGGCGAGGCGTCCGACGGCGCGGAGGGCGTGGCCCGCACCGAGGAGCTGCGGCCCGATG
TCGTCCTCATGGACATCAAGATGCCCGGCACCGACGGGATAGAGGCCCTGCGCAGGCTCCGCGAGCTGGAGAACCCGGCG
AAGATCCTCATCGTCACCAGCTTCACCGAACAGCGCACGGTGGTCCCGGCCCTGCGCGCCGGAGCCTCCGGTTACGTCTA
CAAGGACGTCGACCCGGACGCCCTGGCCGGCGCCATCCGCTCGGTCCACGCCGGGCACGTCCTGCTCCAGCCGGAGGTCG
CGGGCGCGCTCCTCGCCCAGGACGACGCGGGCAGCGGTACGGGGCGGGGGAGCACCCTCACCGAACGCGAGCGGGAAGTG
CTCGGCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGCGCCCTCGTCCTCTCCGAGAAGACGGTCAAGACGCA
CGTGTCGAACATCCTGATGAAACTCGACCTGGCGGACCGCACGCAGGCGGCGCTGTGGGCGGTACGGAACGGGGCGGCGG
GCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E7LU48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.961

96.729

0.425
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.407