Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WID27_RS20565 Genome accession   NZ_CP149796
Coordinates   4731556..4732218 (+) Length   220 a.a.
NCBI ID   WP_019766165.1    Uniprot ID   A0AAD0VF14
Organism   Streptomyces sp. F41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4726556..4737218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS20545 (WID27_20545) kynU 4726778..4728007 (+) 1230 WP_070204325.1 kynureninase -
  WID27_RS20550 (WID27_20550) - 4728176..4729078 (+) 903 WP_070204326.1 alpha/beta hydrolase -
  WID27_RS20555 (WID27_20555) - 4729168..4729989 (+) 822 WP_339152757.1 NAD(P)H-binding protein -
  WID27_RS20560 (WID27_20560) - 4730207..4731559 (+) 1353 WP_339152758.1 histidine kinase -
  WID27_RS20565 (WID27_20565) vraR 4731556..4732218 (+) 663 WP_019766165.1 response regulator transcription factor Regulator
  WID27_RS20570 (WID27_20570) - 4732373..4733578 (+) 1206 WP_339152759.1 cytochrome P450 -
  WID27_RS20575 (WID27_20575) - 4733608..4733946 (-) 339 WP_070204332.1 hypothetical protein -
  WID27_RS20580 (WID27_20580) - 4734058..4734345 (-) 288 WP_053562909.1 DUF1876 domain-containing protein -
  WID27_RS20585 (WID27_20585) - 4734403..4735284 (-) 882 WP_070204333.1 diacylglycerol kinase -
  WID27_RS20590 (WID27_20590) - 4735471..4736754 (+) 1284 WP_339152760.1 adenylosuccinate synthase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23601.46 Da        Isoelectric Point: 4.7962

>NTDB_id=875253 WID27_RS20565 WP_019766165.1 4731556..4732218(+) (vraR) [Streptomyces sp. F41]
MSDIRVLIVDDQMMVREGFSVLLNAMPGITVVGEAVDGRDAVDKVAALLPDVVLMDIRMPGMNGIDATREIVAQVVDAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLITEFSKLAEAPRPPALARVGDLTER
ETEVLVLIAQGLSNAEIASHLIVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=875253 WID27_RS20565 WP_019766165.1 4731556..4732218(+) (vraR) [Streptomyces sp. F41]
ATGAGCGACATCCGCGTCCTGATCGTGGACGACCAGATGATGGTCCGCGAGGGCTTCTCCGTCCTGCTCAACGCCATGCC
GGGGATCACCGTCGTGGGGGAGGCGGTGGACGGCCGGGACGCCGTCGACAAGGTCGCCGCCCTCCTCCCGGACGTCGTCC
TGATGGACATCCGGATGCCGGGGATGAACGGCATCGACGCCACCCGCGAGATCGTCGCGCAGGTCGTGGACGCCAAGGTG
CTGGTCCTGACCACCTTCGACCTGGACGAGTACGTGTACCAGGCGCTGCGGGCCGGGGCCTCGGGCTTCCTCCTCAAGGA
CGCCTCCGCCCGGCAGCTCGCGGACGGCGTACGGGTGGTGGCCTCGGGCGAGGCCCTGCTCGCGCCGACCGTGACCCGGC
GCCTGATCACCGAGTTCTCCAAGCTCGCGGAGGCCCCGAGACCGCCCGCCCTCGCCCGGGTCGGGGACCTCACGGAGCGC
GAGACGGAGGTGCTCGTCCTGATCGCGCAGGGGCTCTCCAACGCGGAGATCGCCTCGCACCTGATCGTCGCCGAGTCCAC
GATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGCCTGCGCGACCGGACGCAGGCGGCGGTGTTCGCGTACGAGG
CGAGGCTGGTGACGCCGGGGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAD0VF14

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.925

97.273

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

41.818

100

0.418