Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   RE468_RS08790 Genome accession   NZ_CP133598
Coordinates   1788167..1789534 (+) Length   455 a.a.
NCBI ID   WP_004869549.1    Uniprot ID   A0A059ZYE0
Organism   MAG: Acidithiobacillus caldus isolate BR_03     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1783167..1794534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE468_RS08775 (RE468_08775) aroE 1784018..1784890 (+) 873 WP_004869542.1 shikimate dehydrogenase -
  RE468_RS08780 (RE468_08780) pilB 1784866..1786572 (+) 1707 WP_004869544.1 type IV-A pilus assembly ATPase PilB Machinery gene
  RE468_RS08785 (RE468_08785) - 1786617..1788170 (+) 1554 WP_004869546.1 PAS domain-containing sensor histidine kinase -
  RE468_RS08790 (RE468_08790) pilR 1788167..1789534 (+) 1368 WP_004869549.1 sigma-54 dependent transcriptional regulator Regulator
  RE468_RS08795 (RE468_08795) - 1789524..1790309 (+) 786 WP_004869552.1 A24 family peptidase -
  RE468_RS08800 (RE468_08800) coaE 1790328..1790915 (+) 588 WP_004869555.1 dephospho-CoA kinase -
  RE468_RS08805 (RE468_08805) zapD 1791020..1791775 (+) 756 WP_309221085.1 cell division protein ZapD -
  RE468_RS08810 (RE468_08810) - 1791820..1792866 (+) 1047 WP_014003070.1 IS630 family transposase -
  RE468_RS08815 (RE468_08815) - 1792893..1793900 (+) 1008 WP_004869560.1 class 1 fructose-bisphosphatase -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49960.73 Da        Isoelectric Point: 6.9080

>NTDB_id=875252 RE468_RS08790 WP_004869549.1 1788167..1789534(+) (pilR) [MAG: Acidithiobacillus caldus isolate BR_03]
MNASVRQRKRALIVDDEPTIVELLGITLEGMGVEVLACHSLAEAFAALGKGPPSLCLTDLRLGDGSGMQLLHKVRELYPQ
VPVAVITAYASAEGAVEAMRAGAFDFMTKPIELARLRRLVSEAIALGELPRESVDLSERLVGESPGMVALRERVRLLGRS
NAPVHIRGESGTGKELVARAIHDASPRREKAFIAVNCGAIPENLMESEFFGAEKGAYSGAVQRREGLFVAANGGTLFLDE
IAELPLTTQVKLLRVLQERVVRPLGGLREQSIDIRLICATHRDLRRMVEEGTFREDLFYRINVVPIEIPPLRERREDIPL
LAQTLLQRLCQRHGRPPANLAPAALAWLSNRDFPGNVRELENLLERALALQSQPLLHREDLEPTAELAVARAPLPAAAPA
ADTALTKRLAEAEWRYLADLQIRLGDRPEEMAKALGISLQSLHLRLARGGSNRDS

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=875252 RE468_RS08790 WP_004869549.1 1788167..1789534(+) (pilR) [MAG: Acidithiobacillus caldus isolate BR_03]
GTGAATGCCAGTGTTCGGCAAAGGAAACGGGCGCTCATCGTCGACGATGAGCCCACCATCGTGGAACTGCTGGGTATCAC
CTTGGAAGGCATGGGGGTCGAGGTCTTGGCTTGCCATAGCCTGGCCGAAGCCTTTGCCGCCCTGGGCAAGGGCCCACCAT
CGCTGTGCCTGACGGATCTGCGCCTGGGCGACGGCTCGGGCATGCAACTCCTGCACAAGGTCCGCGAACTCTACCCGCAG
GTGCCGGTGGCGGTGATCACCGCCTACGCCTCGGCGGAGGGCGCGGTGGAAGCCATGCGCGCCGGCGCCTTCGACTTCAT
GACCAAGCCCATAGAACTGGCACGTCTGCGCCGCCTGGTGAGCGAGGCCATCGCCCTTGGGGAGTTGCCCCGGGAGAGCG
TAGATCTCAGCGAGCGCCTGGTGGGCGAAAGCCCCGGCATGGTGGCCCTGCGCGAGCGCGTTCGCCTGCTGGGACGCAGC
AATGCACCGGTGCATATTCGCGGTGAATCGGGCACCGGCAAGGAACTGGTGGCCCGCGCCATACACGATGCAAGCCCACG
TCGGGAAAAGGCATTCATTGCCGTCAACTGCGGCGCCATCCCGGAAAATCTCATGGAGAGCGAGTTTTTTGGTGCCGAAA
AAGGTGCCTATTCCGGCGCCGTGCAACGGCGGGAAGGACTCTTCGTGGCAGCCAATGGTGGCACGCTCTTTCTCGACGAA
ATAGCCGAACTGCCGCTGACCACGCAGGTGAAACTGCTGCGGGTGCTGCAAGAGCGGGTGGTGCGACCGCTGGGTGGCCT
GCGCGAGCAGAGTATCGATATCCGCCTGATCTGTGCCACCCACCGCGATCTGCGCCGGATGGTGGAGGAGGGCACTTTTC
GCGAAGACCTCTTCTACCGCATCAATGTCGTACCCATAGAGATTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTA
CTGGCGCAAACGCTACTGCAGCGCCTCTGCCAGCGGCACGGACGTCCCCCGGCGAACCTCGCCCCCGCTGCGCTGGCCTG
GCTGTCCAACCGCGATTTCCCGGGCAACGTACGTGAGTTGGAGAACCTCCTGGAGCGGGCGCTCGCCCTACAGTCACAGC
CACTGCTGCACCGGGAAGATCTGGAGCCCACGGCGGAGCTCGCGGTGGCGCGGGCGCCACTGCCCGCTGCCGCACCCGCC
GCGGACACGGCCCTCACCAAGCGCCTGGCCGAGGCAGAGTGGCGCTATCTGGCCGACCTGCAGATCCGCCTTGGCGATCG
ACCCGAGGAAATGGCAAAGGCCCTGGGCATAAGCCTACAATCGCTCCATCTGCGTCTCGCCCGGGGAGGATCGAATCGTG
ATTCCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(12-119)

Sigma-54 interaction domain (Sigma54_activat)

(140-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A059ZYE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

49.224

99.121

0.488
  pilR Acinetobacter baumannii strain A118

40.773

100

0.418